Bio

Clinical Focus


  • Ophthalmology
  • Retina
  • Retinal Diseases
  • Vitreoretinal Surgery
  • Retinal Detachment
  • Macular Degeneration
  • Diabetic Retinopathy
  • Retinal Vein Occlusion
  • Retinal Artery Occlusion
  • Epiretinal Membrane
  • Macular Holes
  • Retinal Drusen
  • Myopia, Degenerative
  • Retinal Telangiectasis

Academic Appointments


Honors & Awards


  • Ronald G. Michels Fellowship Award, The Ronald G. Michels Fellowship Foundation (2013)
  • Heed Fellowship Award, The Heed Ophthalmic Foundation (2012)

Professional Education


  • Board Certification: Ophthalmology, American Board of Ophthalmology (2014)
  • Fellowship:Stanford Medical Center Retina FellowshipCA
  • Residency:Bascom Palmer Eye Institute (2012) FL
  • Medical Education:Stanford University (2008) CA
  • M.Phil., Cambridge University (UK), Neurobiology (2003)
  • BA, Harvard University, Neurobiology (2002)

Publications

Journal Articles


  • Exogenous Fungal Endophthalmitis: An Analysis of Isolates and Susceptibilities to Antifungal Agents Over a 20-Year Period (1990-2010) AMERICAN JOURNAL OF OPHTHALMOLOGY Silva, R. A., Sridhar, J., Miller, D., Wykoff, C. C., Flynn, H. W. 2015; 159 (2): 257-264

    Abstract

    To describe the isolates and susceptibilities to antifungal agents for patients with culture-proven exogenous fungal endophthalmitis.Noncomparative case series.The clinical records of all patients treated for culture-proven exogenous fungal endophthalmitis at a university referral center from 1990 to 2010 were reviewed. Specimens initially used for diagnosis were recovered from the microbiology department and then underwent antifungal sensitivity analysis.The antifungal susceptibilities of 47 fungal isolates from culture-positive fungal endophthalmitis are reported. Included are 14 isolates from yeast and 33 from mold. The mean (±standard deviation) minimum inhibitory concetrations (MICs) for amphotericin B (2.6 ± 3.5 μg/mL), fluconazole (36.9 ± 30.7 μg/mL), and voriconazole (1.9 ± 2.9 μg/mL) are reported. Presumed susceptibility to oral fluconazole, intravenous amphotericin B, intravitreal amphotericin B, oral voriconazole, and intravitreal voriconazole occurred in 34.8%-43.5%, 0-8.3%, 68.8%, 69.8%, and 100% of isolates, respectively.Based on this laboratory study of isolates from exogenous fungal endophthalmitis, intravitreal voriconazole appears to provide the broadest spectrum of antifungal coverage and, as such, may be considered for empiric therapy of endophthalmitis caused by yeast or mold.

    View details for DOI 10.1016/j.ajo.2014.10.027

    View details for Web of Science ID 000348634300007

    View details for PubMedID 25449001

  • Reply. Retina (Philadelphia, Pa.) Moshfeghi, D. M., Silva, R. A., Berrocal, A. M. 2014; 34 (11)

    View details for DOI 10.1097/IAE.0000000000000352

    View details for PubMedID 25333627

  • Reply. Retina (Philadelphia, Pa.) Moshfeghi, D. M., Silva, R. A., Berrocal, A. M. 2014; 34 (8): e23-4

    View details for DOI 10.1097/IAE.0000000000000305

    View details for PubMedID 25054346

  • Antiphospholipid antibody-associated choroidopathy. Eye Silva, R. A., Moshfeghi, D. M. 2014; 28 (6): 773-774

    View details for DOI 10.1038/eye.2014.39

    View details for PubMedID 24603416

  • Retinal breaks due to intravitreal ocriplasmin. Clinical ophthalmology (Auckland, N.Z.) Silva, R. A., Moshfeghi, D. M., Leng, T. 2014; 8: 1591-1594

    Abstract

    Ocriplasmin represents a new treatment option for numerous vitreoretinopathies involving an abnormal vitreomacular interface. While the drug may circumvent the traditional risks of surgical treatment, pharmacologic vitreolysis is not devoid of risk itself. This report presents two cases, one of vitreomacular traction syndrome and the other of a full-thickness macular hole, both of which were treated with an intravitreal injection of ocriplasmin. Notably, in both cases, vitreomacular traction of the macula appears to have been alleviated; however, failure to completely relieve vitreoretinal traction from the peripheral retina generated retinal breaks with one patient eventually developing a macula-involving retinal detachment. Thus, even in instances of 'successful' pharmacologic treatment of vitreomacular traction, continued follow-up evaluation is essential.

    View details for DOI 10.2147/OPTH.S68037

    View details for PubMedID 25210426

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