Bio

Professional Education


  • Bachelor of Science, Jilin University (2008)
  • Doctor of Philosophy, Beijing Normal University (2013)

Stanford Advisors


Publications

All Publications


  • Presynaptic partners of dorsal raphe serotonergic and GABAergic neurons. Neuron Weissbourd, B., Ren, J., DeLoach, K. E., Guenthner, C. J., Miyamichi, K., Luo, L. 2014; 83 (3): 645-662

    Abstract

    The serotonin system powerfully modulates physiology and behavior in health and disease, yet the circuit mechanisms underlying serotonin neuron activity are poorly understood. The major source of forebrain serotonergic innervation is from the dorsal raphe nucleus (DR), which contains both serotonin and GABA neurons. Using viral tracing combined with electrophysiology, we found that GABA and serotonin neurons in the DR receive excitatory, inhibitory, and peptidergic inputs from the same specific brain regions. Embedded in this overall similarity are important differences. Serotonin neurons are more likely to receive synaptic inputs from anterior neocortex while GABA neurons receive disproportionally higher input from the central amygdala. Local input mapping revealed extensive serotonin-serotonin as well as GABA-serotonin connectivity with a distinct spatial organization. Covariance analysis suggests heterogeneity of both serotonin and GABA neurons with respect to the inputs they receive. These analyses provide a foundation for further functional dissection of the serotonin system.

    View details for DOI 10.1016/j.neuron.2014.06.024

    View details for PubMedID 25102560

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