Honors & Awards

  • JDRF Postdoctoral Fellowship Award, Juvenile Diabetes Research Foundation (2014-15)
  • NIH Loan Repayment Program Award, National Institute of Health (2013-14)
  • Stephen Bechtel Endowed Postdoctoral Fellow, Stanford Child Health Research Institute (2013-15)
  • Alpha Omega Alpha Medical Honor Society, George Washington University AOA Housestaff Inductee (2012)
  • David C. Leach Award, ACGME (2012)
  • Resident Physician Community Service Award, AAMC (2012)
  • Medical Student Teaching Award, The George Washington University School of Medicine (2011)
  • James A. Knight Award for Excellence in Humanities in Medicine, Medical Humanities Department at Texas A&M COM (2008)
  • Gold Humanism Honor Society Inductee, Gold Humanism Honor Society (2007)
  • AAMC Medicine in the Community Grant Recipient, AAMC, sponsored by Pfizer, Inc. (2006)
  • Phi Beta Kappa Inductee, Baylor University (2003)
  • Most Outstanding Student in Political Science, Baylor University (2003)
  • Presidential Scholar, Baylor University (1999-2003)

Professional Education

  • Doctor of Medicine, Texas A&M University College Station (2008)
  • Bachelor of Arts, Baylor University (2003)

Stanford Advisors


Graduate and Fellowship Programs

  • Pediatric Endocrinology (Fellowship Program)


Journal Articles

  • Overnight glucose control with an automated, unified safety system in children and adolescents with type 1 diabetes at diabetes cAMP. Diabetes care Ly, T. T., Breton, M. D., Keith-Hynes, P., De Salvo, D., Clinton, P., Benassi, K., Mize, B., Chernavvsky, D., Place, J., Wilson, D. M., Kovatchev, B. P., Buckingham, B. A. 2014; 37 (8): 2310-2316


    To determine the safety and efficacy of an automated unified safety system (USS) in providing overnight closed-loop (OCL) control in children and adolescents with type 1 diabetes attending diabetes summer camps.RESEARCH DESIGN AND METHODS: The Diabetes Assistant (DIAS) USS used the Dexcom G4P glucose sensor (Dexcom) and t:slim insulin pump (Tandem Diabetes Care). An initial inpatient study was completed for 12 participants to evaluate safety. For the main camp study, 20 participants with type 1 diabetes were randomized to either OCL or sensor-augmented therapy (control conditions) per night over the course of a 5- to 6-day diabetes camp.RESULTS: Subjects completed 54 OCL nights and 52 control nights. On an intention-to-treat basis, with glucose data analyzed regardless of system status, the median percent time in range, from 70-150 mg/dL, was 62% (29, 87) for OCL nights versus 55% (25, 80) for sensor-augmented pump therapy (P = 0.233). A per-protocol analysis allowed for assessment of algorithm performance. The median percent time in range, from 70-150 mg/dL, was 73% (50, 89) for OCL nights (n = 41) versus 52% (24, 83) for control conditions (n = 39) (P = 0.037). There was less time spent in the hypoglycemic range <50, <60, and <70 mg/dL during OCL compared with the control period (P = 0.019, P = 0.009, and P = 0.023, respectively).CONCLUSIONS: The DIAS USS algorithm is effective in improving time spent in range as well as reducing nocturnal hypoglycemia during the overnight period in children and adolescents with type 1 diabetes in a diabetes camp setting.

    View details for DOI 10.2337/dc14-0147

    View details for PubMedID 24879841

  • Accuracy Evaluation of Blood Glucose Monitoring Systems in Children on Overnight Closed-Loop Control. Journal of diabetes science and technology DeSalvo, D. J., Shanmugham, S., Ly, T. T., Wilson, D. M., Buckingham, B. A. 2014


    This pilot study evaluated the difference in accuracy between the Bayer Contour® Next (CN) and HemoCue® (HC) glucose monitoring systems in children with type 1 diabetes participating in overnight closed-loop studies. Subjects aged 10-18 years old were admitted to a clinical research center and glucose values were obtained every 30 minutes overnight. Glucose values were measured using whole blood samples for CN and HC readings and results were compared to Yellow Springs Instrument (YSI) reference values obtained with plasma from the same sample. System accuracy was compared using mean absolute relative difference (MARD) and International Organization for Standardization (ISO) accuracy standards. A total of 28 subjects were enrolled in the study. Glucose measurements were evaluated at 457 time points. CN performed better than HC with an average MARD of 3.13% compared to 10.73% for HC (P < .001). With a limited sample size, CN met ISO criteria (2003 and 2013) at all glucose ranges while HC did not. CN performed very well, and would make an excellent meter for future closed-loop studies outside of a research center.

    View details for DOI 10.1177/1932296814532238

    View details for PubMedID 24876427

  • Continuous glucose monitoring: current use and future directions. Current diabetes reports DeSalvo, D., Buckingham, B. 2013; 13 (5): 657-662


    Continuous glucose monitoring (CGM) is an emerging technology that provides a continuous measure of interstitial glucose levels. In addition to providing a more complete pattern of glucose excursions, CGMs utilize real-time alarms for thresholds and predictions of hypo- and hyperglycemia, as well as rate of change alarms for rapid glycemic excursions. CGM users have been able to improve glycemic control without increasing their risk of hypoglycemia. Sensor accuracy, reliability, and wearability are important challenges to CGM success and are critical to the development of an artificial pancreas (or closed-loop system).

    View details for DOI 10.1007/s11892-013-0398-4

    View details for PubMedID 23943230

  • In children with premature adrenarche, bone age advancement by 2 or more years is common and generally benign JOURNAL OF PEDIATRIC ENDOCRINOLOGY & METABOLISM DeSalvo, D. J., Mehra, R., Vaidyanathan, P., Kaplowitz, P. B. 2013; 26 (3-4): 215-221


    Premature adrenarche (PA) is often associated with bone age (BA) advanced by ≥2 years, which increases the concern for underlying pathology, but the frequency and clinical significance of this is unknown. Our objective was to identify the proportion of PA patients with very advanced BA and normal BA and compare the clinical characteristics of the two groups.Charts of 427 patients aged 5-9 years, referred for early puberty over a 2-year period, were reviewed for clinical diagnosis, growth, parental heights, hormone levels and BA. We divided the PA patients into three separate groups based on degree of BA advancement. Predicted adult heights (PAH) were calculated and compared to mid-parental target height (TH).Of 427 patients, 266 (62%) had PA (82% female). Of the 121 with BA, 30.6% had very advanced BA (≥2 years) and this group was taller (Ht SD+1.72 vs. +0.72, p<0.00001) and had higher BMI (SD+1.70 vs. +0.99, p<0.001) than patients with BA advanced by <1 year, but hormone levels were quite similar. Mean PAH was slightly less than TH for patients with very advanced BA, but there were no girls with PAH <60 inches 152.4 cm or boys with PAH <65 inches 165.1 cm in height.Very advanced BA is common in PA, and patients were significantly taller and more overweight than their peers. The impact of advanced BA on PAH appears to be minor. We question the need for ordering a BA in patients with PA, and suggest that extensive testing is unnecessary simply because of advanced BA.

    View details for DOI 10.1515/jpem-2012-0283

    View details for Web of Science ID 000316898800005

    View details for PubMedID 23744298

  • Remote Glucose Monitoring in Camp Setting Reduces the Risk of Prolonged Nocturnal Hypoglycemia Diabetes Technology & Therapeutics DeSalvo, D. J., et al 2013
  • A Learner-Centered Diabetes Management Curriculum Reducing resident errors on an inpatient diabetes pathway DIABETES CARE DeSalvo, D. J., Greenberg, L. W., Henderson, C. L., Cogen, F. R. 2012; 35 (11): 2188-2193


    Diabetes errors, particularly insulin administration errors, can lead to complications and death in the pediatric inpatient setting. Despite a lecture-format curriculum on diabetes management at our children's hospital, resident diabetes-related errors persisted. We hypothesized that a multifaceted, learner-centered diabetes curriculum would help reduce pathway errors.The 8-week curricular intervention consisted of 1) an online tutorial addressing residents' baseline diabetes management knowledge, 2) an interactive diabetes pathway discussion, 3) a learner-initiated diabetes question and answer session, and 4) a case presentation featuring embedded pathway errors for residents to recognize, resolve, and prevent. Errors in the 9 months before the intervention, as identified through an incident reporting system, were compared with those in the 10 months afterward, with errors classified as relating to insulin, communication, intravenous fluids, nutrition, and discharge delay.Before the curricular intervention, resident errors occurred in 28 patients (19.4% of 144 diabetes admissions) over 9 months. After the intervention, resident errors occurred in 11 patients (6.6% of 166 diabetes admissions) over 10 months, representing a statistically significant (P = 0.0007) decrease in patients with errors from before intervention to after intervention. Throughout the study, the errors were distributed into the categories as follows: insulin, 43.8%; communication, 39.6%; intravenous fluids, 14.6%; nutrition, 0%; and discharge delay, 2.1%.An interactive learner-centered diabetes curriculum for pediatric residents can be effective in reducing inpatient diabetes errors in a tertiary children's hospital. This educational model promoting proactive learning has implications for decreasing errors across other medical disciplines.

    View details for DOI 10.2337/dc12-0450

    View details for Web of Science ID 000311424100018

    View details for PubMedID 22875227

  • Five-Year Follow-Up of Carpal Tunnel Release in Patients Over Age 65 JOURNAL OF HAND SURGERY-AMERICAN VOLUME Weber, R. A., DeSalvo, D. J., Rude, M. J. 2010; 35A (2): 207-211
  • Cholestasis secondary to panhypopituitarism in an infant JOURNAL OF THE NATIONAL MEDICAL ASSOCIATION DeSalvo, D., Pohl, J. F., Wilson, D. P., Bryant, W., Easley, D., Greene, J., Santiago, J. 2008; 100 (3): 342-344


    Cholestasis occurring in infancy should be evaluated completely to exclude hepatic as well as endocrine or metabolic causes. A rapid diagnosis should be made to ensure that hepatic and neurologic complications are prevented. We describe a rare case of infant cholestasis due to panhypopituitarism resulting in hypoglycemia and liver biopsy findings consistent with bile duct paucity. Existing bile ducts were noted to be small, and electron microscopy demonstrated diminutive and atrophied biliary cells with a diminished bile duct lumen size. Hypoglycemia and cholestasis resolved with treatment of the underlying panhypopituitarism. Panhypopituitarism should be considered in any infant who presents with cholestasis, hypoglycemia, and other manifestations of pituitary malfunction. Growth hormone deficiency may affect bile duct formation as demonstrated in this patient.

    View details for Web of Science ID 000254549500010

    View details for PubMedID 18390029

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