School of Medicine
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Postdoctoral Research fellow, Molecular and Cellular Physiology
Bio I am a Postdoc in Dr. Goodman’s lab. Here we investigate (mechano-) sensation of the nematode C. elegans. I am especially interested in the touch response and in the chemo-sensation learning behavior. For these studies I use:
- Fluorescence microscopy
- Microfluidic chips
- Calcium imaging
- Image and data analysis with ImageJ and Python
Before coming to Stanford I did my Ph.D. at the University of Cologne, Germany. For this I did my doctoral research at Prof. Kaupp’s lab at the research center caesar in Bonn, Germany. The title of my thesis is: "Single-molecule studies of the ligand binding of a hyperpolarization-activated and cyclic nucleotide-gated ion channel". For these studies I used:
- Fluorescence, single-molecule microscopy (TIRF)
- Image analysis with ImageJ
- Fluorescence lifetime spectroscopy
Before starting my doctoral research I studied physics, with focus on optics, at the Leibniz University Hannover, Germany. I did my diploma at Prof. Heisterkamp’s lab at the Laser Center Hannover, Germany. The title of my thesis is: "Plasmonic-based laser transfection". For these studies I used:
- fs laser pulses
- Plasmonics at gold nanoparticels
- Two-photon microscopy
Assistant Professor of Molecular and Cellular Physiology
Current Research and Scholarly Interests We are interested in the structure, dynamics and function of eukaryotic transport proteins mediating ions and major nutrients crossing the membrane, the kinetics and regulation of transport processes, the catalytic mechanism of membrane embedded enzymes and the development of small molecule modulators based on the structure and function of membrane proteins.
Professor of Molecular and Cellular Physiology and of Structural Biology
Current Research and Scholarly Interests Structural and functional studies of transmembrane receptor interactions with their ligands in systems relevant to human health and disease - primarily in immunity, infection, and neurobiology. We study these problems using protein engineering, structural, biochemical, and combinatorial biology approaches.
Miriam B. Goodman
Associate Professor of Molecular and Cellular Physiology and, by courtesy, of Mechanical Engineering
Current Research and Scholarly Interests We study the molecular events that give rise to the sensation of touch and temperature in C. elegans. To do this, we use a combination of quantitative behavioral analysis, genetics, in vivo electrophysiology, and heterologous expression of ion channels. We also collaborate with Pruitt's group in Mechanical Engineering to develop and fabricate novel devices for the study of sensory transduction.
Ph.D. Student in Molecular and Cellular Physiology, admitted Autumn 2013
Current Research and Scholarly Interests Engineering and development of small protein cancer immunotherapeutics.