School of Medicine
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Associate Professor of Neurosurgery
Current Research and Scholarly Interests For most areas of the mammalian brain, the production of new nerve cells or neurons is restricted to fetal development. However, there are exceptions to the rule. Some areas of the brain continue to make new neurons throughout life. This neurogenesis is mediated by neural stem cells and our research goals are to understand how stem cell activity and fate are controlled. Ultimately, we hope to harness the nascent potential of stem cells to treat neurological injury and disease.
Henry Dreyfus Professor of Chemistry and Professor, by courtesy, of Structural Biology
Current Research and Scholarly Interests The central theme of our research is to develop and apply novel theoretical methods to understand the physical properties of biological molecules, such as proteins, nucleic acids, lipid membranes, and small molecule therapeutics (eg protein folding or lipid vesicle fusion). As these phenomena are complex, my research employs novel theoretical and computational techniques. We apply these methods to develop novel therapeutics for protein misfolding diseases, such as Alzheimer's Disease.
Alan C. Pao
Assistant Professor of Medicine (Nephrology) at the Palo Alto Veterans Affairs Health Care System
Current Research and Scholarly Interests We are interested in the hormonal and signal transduction pathways that control epithelial ion transport. Our model system involves tight epithelia, typically found in the distal nephron of the kidney. Clinical implications of our work include a better understanding of the pathogenesis of salt-sensitive hypertension and hypertension associated with the insulin resistance syndrome.
Assistant Professor of Pediatrics (Gastroenterology) at the Lucile Salter Packard Children's Hospital
Current Research and Scholarly Interests I am a clinician investigator in the Department of Pediatrics (Gastroenterology) at Stanford University, and faculty associate with Stanford Health Policy. My current NIH-funded research focus is on the pharmaco-economics of inflammatory bowel disease (IBD). The purpose of my research endeavors is to inform clinical practice by identifying optimal, patient-specific strategies in the treatment of IBD.
Karen J. Parker, PhD
Associate Professor (Research) of Psychiatry and Behavioral Sciences (Child and Adolescent Psychiatry and Child Development)
Current Research and Scholarly Interests The Parker Lab conducts research on biomarkers of, and therapeutic testing for, social impairments in animal models and in patients with social deficit disorders.
George DeForest Barnett Professor in Medicine and Professor of Health Research and Policy (Epidemiology)
Current Research and Scholarly Interests I am an infectious diseases epidemiologist who has done large field studies in both the US and developing countries. We research the long-term consequences of chronic interactions between the human host and the microbial world. My lab has done fundamental work establishing the role of H. pylori in causing disease and understanding its epidemiology. Currently, our research dissects how and when children first encounter microbes and the long term effects of these exposures on health.
Sergiu P. Pasca
Assistant Professor of Psychiatry and Behavioral Sciences (Sleep Disorder/Sleep Center)
Current Research and Scholarly Interests Our lab is interested in deciphering the molecular and cellular mechanisms of neuropsychiatric disorders. To achieve this, we employ a multidisciplinary approach involving human genetics, molecular and developmental neurobiology, rodent disease models and neural cells differentiated from patient-derived induced pluripotent stem cells. We are also developing methods for generating specific classes of neurons from human stem cells and state-of-the-art tools for probing disease-relevant cellular endophenotypes. Our ultimate objective is to identify novel and reliable drug targets for neuropsychiatric disorders.
Professor of Anesthesiology, Perioperative and Pain Medicine
Current Research and Scholarly Interests The laboratory develops and uses state of the art genomic methods to identify genetic factors affecting disease susceptibility, and to translate these findings into new treatments. We have developed a more efficient method for performing mouse genetic analysis, which has been used to analyze the genetic basis for 16 different biomedical traits. We are developing novel methods, and have developed a novel experimental platform that replaces mouse liver with functioning human liver tissue.
Kevin and Michelle Douglas Professor in the School of Humanities and Sciences
Current Research and Scholarly Interests Evolution of genomes and population genomics of adaptation and variation