School of Medicine
Showing 1-10 of 23 Results
Professor of Genetics
Current Research and Scholarly Interests My lab is developing innovative gene and stem cell therapies for genetic diseases, with a focus on gene therapy and regenerative medicine.
We have created novel methods for inserting therapeutic genes into the chromosomes at specific places by using homologous recombination and recombinase enzymes.
We are working on 3 forms of muscular dystrophy.
We created induced pluripotent stem cells from patient fibroblasts, added therapeutic genes, differentiated, and engrafted the cells.
Assistant Professor of Bioengineering and, by courtesy, of Mechanical Engineering
Current Research and Scholarly Interests The Camarillo Lab is currently instrumenting Stanford athletes with inertial sensors to investigate the mechanism of concussion. Additionally, the lab is researching cell mechanics for regenerative medicine. We are developing a quantitative, noninvasive and early measure of viability in order to allow clinicians to transfer the single most viable embryo. Other research area is in medical instrumentation as it pertains to robotic catheterization for curing cardiac arrhythmia.
Assistant Professor of Microbiology and Immunology
Current Research and Scholarly Interests Our research focuses on the identification of host genes that play critical roles in the pathogenesis of infectious agents including viruses. We use haploid genetic screens in human cells as an efficient approach to perform loss-of-function studies. Besides obtaining fundamental insights on how viruses hijack cellular processes and on host defense mechanisms, it may also facilitate the development of new therapeutic strategies.
Associate Professor (Research) of Pediatrics (Neonatology)
Current Research and Scholarly Interests Our research focuses on epidemiologic studies related to maternal and child health. Current projects address congenital anomalies of craniofacial, urogenital, musculoskeletal and central nervous system structures and how they relate to genetics, nutrition, stress, and environmental contaminants. Physiologic pathways encompassed by these studies include one-carbon metabolism, oxidative stress, HPA axis activation, and sex steroid metabolism. In particular, we are interested in discovering how environmental factors and genetic susceptibility may interact to affect these pathways and impact risks of these outcomes. Other active projects include investigations into the etiology of preterm delivery and stillbirth, and factors affecting the care and outcomes of infants with birth defects.
Associate Professor of Anesthesiology, Perioperative and Pain Medicine at the Stanford University Medical Center
Current Research and Scholarly Interests My main research interest is in clinical and translational research related to cesarean delivery and labor analgesia as well as maternal-fetal pharmacokinetics and pharmacodynamics drug modeling.
Anne Lynn S. Chang, MD
Assistant Professor of Dermatology at the Stanford University Medical Center
Current Research and Scholarly Interests I have two main research interests:
1) to better understand and treat patients with aggressive basal cell carcinomas
2) to better understand the genetic and epigenetic mechanisms of healthy human skin aging and to translate these insights into better care of skin diseases enriched in older patients particularly skin cancer and rosacea
Howard Y. Chang
Professor of Dermatology
Current Research and Scholarly Interests Our research is focused on how the activities of hundreds or even thousands of genes (gene parties) are coordinated to achieve biological meaning. We have pioneered methods to predict, dissect, and control large-scale gene regulatory programs; these methods have provided insights into human development, cancer, and aging.
James K. Chen
Associate Professor of Chemical and Systems Biology and of Developmental Biology and, by courtesy, of Chemistry
Current Research and Scholarly Interests Our laboratory combines synthetic chemistry and developmental biology to investigate the molecular events that regulate embryonic patterning, tissue regeneration, and tumorigenesis. We are currently using genetic and small-molecule approaches to study the molecular mechanisms of Hedgehog signaling, and we are developing chemical technologies to perturb and observe the genetic programs that underlie vertebrate development.
Alan G. Cheng
Associate Professor of Otolaryngology - Head and Neck Surgery and, by courtesy, of Pediatrics
Current Research and Scholarly Interests Active Wnt signaling maintains somatic stem cells in many organ systems. Using Wnt target genes as markers, we have characterized distinct cell populations with stem cell behavior in the inner ear, an organ thought to be terminally differentiated. Ongoing work focuses on delineating the developing significance of these putative stem/progenitor cells and their behavior after damage.