School of Medicine
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Frank Lee and Carol Hall Professor and Professor of Genetics
Current Research and Scholarly Interests We use the tools of genetics, microscopy, and biochemistry to understand fundamental questions of cell biology: How are cells organized by the cytoskeleton? How do the centrosome and cilium control cell control cell signaling? How is cell division coordinated with duplication of the centrosome, and what goes wrong in cancer cells defective in this coordination?
Marcia L. Stefanick, Ph.D.
Professor (Research) of Medicine (Stanford Prevention Research Center) and of Obstetrics and Gynecology
Current Research and Scholarly Interests Marcia Stefanick, Ph.D a Professor of Medicine at the Stanford Prevention Research Center, (SPRC) and Professor of Obstetrics and Gynecology, Stanford University School of Medicine.
Dr. Stefanicks research focuses on chronic disease prevention (particularly, heart disease, breast cancer, osteoporosis, and dementia) in both women and men. Her work on the effects of menopausal hormones on cardiovascular and other health outcomes in mostly healthy postmenopausal women (in the Womens Health Initiative, WHI), in women with established heart disease, (the Heart and Estrogen-progesterone Replacement Study, HERS), and in peri-menopausal and early post-menopausal women (the Postmenopausal Estrogen and Progesterone Interventions, PEPI) trials has been widely disseminated both nationally and internationally. She was also the principal investigator of two large diet trials focusing on the role of a low-fat eating pattern (including increased vegetables & fruits) on preventing breast cancer (WHI) and recurrence (Womens Healthy Eating and Living, WHEL, trial) and she conducted several medium-sized diet, exercise, and weight control trials focused on heart disease risk and body composition that have influenced national guidelines. [She is currently writing a proposal for a large national trial of physical activity in older women with cardiovascular outcomes, not just risk factors.] Her current passion is the study of Sex (and Gender) Differences in Human Physiology and Disease, the title of a course she teaches in Stanfords Human Biology program, in addition to a course entitled: Current Topics and Controversies in Womens Health. Dr. Stefanick also plays major leadership roles in Stanfords Cardiovascular Institutes Womens Heart Health Program and Stanford Cancer Institutes Cancer Prevention and Control Program.
Dr. Stefanick obtained her B.A. in biology from the University of Pennsylvania, Philadelphia, PA (1974), then pursued her interest in hormone and sex difference research at the Oregon Regional Primate Research Center, after which she obtained her PhD in Physiology at Stanford University, focusing on reproductive physiology and neuroendocrinology with exercise physiology as a secondary focus. Her commitment to human research directed her to a post-doctoral fellowship in Cardiovascular Disease Prevention at SPRC, which has been her academic home for nearly 30 years.
Clinical Assistant Professor, Pediatrics - Critical Care
Current Research and Scholarly Interests My research interests focus on using dissemination and implementation science tools to study and enhance care provided to patients in the pediatric ICU. I have a background in human factors research and in implementation science and am also interested in clinical effectiveness and outcomes in the PICU.
Clinical Assistant Professor, Orthopaedic Surgery
Bio Dr. Steffner specializes in the evaluation, diagnosis, and treatment of bone and soft tissue tumors in pediatric and adult patients. This includes primary bone and soft tissue sarcomas, locally active conditions such as giant cell tumor, aneurysmal bone cyst, and chondroblastoma, as well as impending and pathologic fractures from metastatic carcinoma, multiple myeloma, and lymphoma. He works with an exceptional multidisciplinary group of physicians at the Stanford Cancer Center to provide coordinated, highly specialized treatment strategies. Dr. Steffner also maintains an interest in orthopaedic fracture surgery from trauma.
Research interests include large database outcome studies for rare tumors and metastatic disease, basic science collaboration on systemic treatment strategies for soft tissue sarcoma, and the development of novel surgical techniques.
Gary K. Steinberg, MD, PhD
Bernard and Ronni Lacroute-William Randolph Hearst Professor in Neurosurgery and Neurosciences and Professor, by courtesy, of Neurology
Current Research and Scholarly Interests Our laboratory investigates the pathophysiology and treatment of cerebral ischemia, and methods to restore neurologic function after stroke. Treatment strategies include brain hypothermia, stem cell transplantation and optogenetic stimulation. Our clinical research develops innovative surgical, endovascular and radiosurgical approaches for treating difficult intracranial aneurysms, complex vascular malformations and occlusive disease, including Moyamoya disease, as well as stem cell transplant.
Dr. med. Hans Steiner
Professor of Psychiatry and Behavioral Sciences at the Lucile Salter Packard Children's Hospital, Emeritus
Current Research and Scholarly Interests Humanistic Medicine and Psychiatry; creative writing as a tool for healing
Psycholinguistics to study the diagnostic and treatment effects of expressive writing and narrative
Human stress response, emotional activation, conscious and unconscious self regulation
Developmental Psychiatry, disruptive behavior disorders, psychiatric trauma related psychopathology Psychosomatic Medicine, Eating Disorders, Pain
Sport Psychology/Psychiatry; Elite Athletes; mental toughness and focus
Lawrence Steinman, MD
George A. Zimmermann Professor and Professor of Pediatrics
Current Research and Scholarly Interests Our laboratory is dedicated to understanding the pathogenesis of autoimmune diseases, particularly multiple sclerosis. We have developed several new therapies for autoimmunity, including some in Phase 2 clinical trials, as well as one approved drug, natalizumab. We have developed microarray technology for detecting autoantibodies to myelin proteins and lipids. We employ a diverse range of molecular and celluar approaches to trying to understand multiple sclerosis.
Professor of Genetics
Current Research and Scholarly Interests We apply diverse genomic approaches to understand how genetic variation affects health and disease by: 1) functional and mechanistic analyses of gene regulation, 2) studies of meiotic recombination and inheritance, 3) analyses of genetic and environmental interactions, and 4) characterization of diseases in human cells and model organisms. We integrate wet lab and computational genomic, transcriptomic, proteomic and metabolic approaches, and develop technologies to enable personalized medicine.