The laboratory focuses on signaling in the immune system and study of host processes that HIV-1 exploits. Control of apoptosis, autoimmunity, angiogenesis, retrovirology, and blockade of HIV-1 infection are prominent in our studies.

We use advanced Flow Cytometric analysis (FACS) of phosphoproteins in single cells and dominant effector genetics to achieve many of our goals. For this we have developed a range of FACS assays, cDNA and peptide expression systems using viruses, and single-cell genetic selections, to study pathways of interest to us.

For more information, please visit the Nolan Lab web site.