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A list of articles recently published by MIPS faculty and staff members.

Authors Pub. Title Pub. Name Year Vol. Issue Pages
Habte F, Olcott PD, Levin CS, Foudray AM  Prototype Parallel Readout System for Position Sensitive PMT Based Gamma-Ray Imaging Systems IEEE Trans. Nucl. Sci. 2007  54  60-65 
Habte F, Olcott PD, Foudray AM, Levin CS, Zhang J, Chinn G  Simulation and Measurement of Gamma-Ray and Annihilation Photon Imaging Detectors IEEE Trans. Nucl. Sci. 2007      in press 
Olcott PD, Levin CS  Image Processing Algorithms to Facilitate and Enhance Sentinel Node Detection Using a Hand-Held Gamma Ray Camera in Surgical Breast Cancer Staging Physica Medica 2007  21    99-101 
Olcott PD, Habte F, Levin CS, Foudray AM  Performance Characterization of a Miniature, High Sensitivity Gamma-Ray Camera IEEE Trans. Nucl. Sci. 2007  54  11492-1497 
Foudray AM, Habte F, Chinn G, Zhang J, Levin CS, Olcott PD  Optimization of a Cylindrical PET Breast Imaging System Comprised of Position Sensitive Avalanche Photodiodes Utilizing Monte Carlo Simulation Physica Medica 2007      in press 
Hickerson RP, Smith FJD, Reeves RE, Contag CH, Leake D, Leachman SA, Milstone LM, McLean WHI, Kaspar RL  Single Nucleotide-Specific SiRNA Targeting in a Dominant Negative Skin Model Journal of Investigative Dermatology 2007      in press 
Keren S, Gheysens O, Levin CS, Gambhir SS  Characterization of a Small Animal Time-Domain Fluorescence Tomography Imaging System IEEE Trans. Medical Imaging 2007      Undergoing Revision 
Keren S, Gheysens O, Levin CS, Gambhir SS  Characterization of a Small Animal Time-Domain Fluorescence Tomography Imaging System IEEE Trans. Medical Imaging 2007      Undergoing Revision 
Liu Z, Chen K, Davis C, Sherlock S, Cao Q, Chen X, Dai H  Drug delivery with carbon nanotubes for in vivo cancer treatment Cancer Res. 2008  68  16  6552-6560 
Cai W, Olafsen T, Zhang X, Cao Q, Gambhir SS, Williams LE, Wu AM, Chen X  Positron Emission Tomography Imaging of Colorectal Cancer in Xenograft-Bearing Mice Using 18F-Labeled T84.66 Anti-CEA Diabody J. Nucl. Med. 2007  48    304-310 
Cai W, Olafsen T, Zhang X, Cao Q, Gambhir SS, Williams LE, Wu AM, Chen X  Positron Emission Tomography Imaging of Colorectal Cancer in Xenograft-Bearing Mice Using 18F-Labeled T84.66 Anti-CEA Diabody J. Nucl. Med. 2007  48    304-310 
Li Z-B, Cai W, Chen X  Biocompatible Quantum Dots for In vivo Imaging J. Nanosci. Nanotechnol. 2007    2567-2581 
Liu Z, Cai W, He L, Nakayama N, Chen K, Sun X, Chen X, Dai H  In-vivo biodistribution and highly efficient tumor targeting of carbon nanotubes in mice Nat. Nanotechnol. 2007    47-52 
Hsu AR, Cai W, Veeravagu A, Chen K, Vogel H, Hou LC, Mohamedali KA, Rosenblum M, Tse V, and Chen X  In Vivo Multi-Modality Molecular Imaging of Orthotopic Glioblastoma Tumor Growth Inhibition Using Vascular-Targeting Fusion Toxin VEGF121/rGel Journal of Nuclear Medicine 2007  48  445-454 
Cai W, Chen K, He L, Cao Q, Koong A, Chen X  Quantitative PET imaging of EGFR expression in xenograft-bearing mice using 64Cu-labeled Cetuximab, a chimeric anti-EGFR monoclonal antibody Eur. J. Nucl. Med. Mol. Imaging 2007  34  850-8 
Veeravagu A, Hsu AR, Cai W, Hou LC, Tse V, Chen X  Vascular Endothelial Growth Factor and Vascular Endothelial Growth Factor Receptor as Anti-Angiogenic Agents in Cancer Therapy Recent Patents on Anti-Cancer Drug Discovery 2007  59-71 
Hsu AR, Veeravagu A, Cai W, Hou LC, Tse V, Chen X  Integrin avb3 Antagonists for Anti-Angiogenic Cancer Treatment Recent Patents on Anti-Cancer Drug Discovery 2007  143-160 
Li Z-B, Cai W, Cao Q, Chen K, Wu Z, He L, Chen X.  64Cu-Labeled Tetrameric and Octameric RGD Peptides for MicroPET Imaging of Tumor alpha(v)beta(3) Integrin Expression J Nucl Med 2007  48  1162-1171 
Wu Z, Li Z-B, Cai W, He L, Chin FT, Li F, Chen X.  18F-labeled mini-PEG spacered RGD dimer (18F-FPRGD2): synthesis and microPET imaging of alpha(v)beta(3) integrin expression Eur. J. Nucl. Med. Mol. Imaging. 2007  34  11  1823-1831 
Cheng Z, Xiong Z, Subbarayan M, Chen X, Gambhir SS.  (64)Cu-Labeled Alpha-Melanocyte-Stimulating Hormone Analog for MicroPET Imaging of Melanocortin 1 Receptor Expression. Bioconjug Chem. 2007  [Epub ahead of print]     
Cheng Z, Zhang L, Graves E, Xiong Z, Dandekar M, Chen X, Gambhir SS  Small-animal PET of melanocortin 1 receptor expression using a 18F-labeled alpha-melanocyte-stimulating hormone analog J Nucl Med 2007  48  987-94 
Kutschka I, Chen IY, Kofidis T, von Degenfeld G, Sheikh AY, Hendry SL, Hoyt G, Pearl J, Blau HM, Gambhir SS, Robbins RC  In vivo optical bioluminescence imaging of collagen-supported cardiac cell grafts J Heart Lung Transplant 2007  26  273-80 
Kutschka I, Chen IY, Kofidis T, von Degenfeld G, Sheikh AY, Hendry SL, Hoyt G, Pearl J, Blau HM, Gambhir SS, Robbins RC  In vivo optical bioluminescence imaging of collagen-supported cardiac cell grafts J Heart Lung Transplant 2007  26  273-80 
Hsu AR and Chen X  Biomedical Applications of Quantum Dot Semiconductor Nanoparticles Encyclopedia of Nanoscience and Nanotechnology 2007  (Editor, Nalwa HS)  American Scientific Publishers   
Veervagu A, Hou LC, Hsu AR, Cai W, Greve JM, Hoang S, Chen X, and Tse V  The Temporal Correlation of Dynamic Contrast Enhanced Magnetic Resonance Imaging with Tumor Angiogenesis in a Murine Glioblastoma Model Neurological Research 2008  30  952-959 
Massoud TF, Paulmurugan R, De A, Ray P and Gambhir SS  Reporter gene imaging of protein–protein interactions in living subjects. Current Opinion in Biotechnology 2007  18    1-7 
Deroose CM, De A, Loening AM, Chow PL, Ray P, Chatziioannou AF, and Gambhir SS   Multimodality Imaging of Tumor Xenografts and Metastasis in Mice with Combined Micro Positron Emission Tomography, Small Animal Computed Tomography and Bioluminescence Imaging Journal Nuclear Medicine 2007  48    295-303 
Cao Q, Cai W, Li Z-B, Chen K, He L, Li H-C, Hui M, Chen X  PET of Acute and Chronic Inflammation in Living Mice Eur J Nucl Med Mol Imaging 2007  34  11  1832-1842 
Cai W, Chen X  Multimodality imaging of vascular endothelial growth factor and vascular endothelial growth factor receptor expression Front Biosci 2007      in press 
Zhang J, Olcott PD, Chinn G, Foudray AMK, Levin CS  Study of the Performance of a Novel 1 mm Resolution Dual-Panel PET Camera Design Dedicated to Breast Cancer Imaging Using Monte Carlo Simulation Medical Physics 2007  34  689-702 
Zhang J, Olcott PD, Levin CS  A New Positioning Algorithm for Position-Sensitive Avalanche Photodiodes IEEE Trans. Nucl. Sci. 2007  54  433-437 
Zhang J, Foudray AMK, Olcott PD, Levin CS  Performance Characterization of a Novel Thin Position-Sensitive Avalanche Photodiode for High Resolution Positron Emission Tomography IEEE Trans. Nucl. Sci. 2007  54  415-421 
Zhang J, Olcott PD, Levin CS  Monte Carlo Simulation Study on the Performance of a Novel Dual-Panel PET Camera Dedicated to Breast Cancer Imaging Medical Physics 2007      in press 
Habte F, Foudray AMK, Olcott PD, Levin CS  Effects of System Geometry and Other Physical Factors on Photon Sensitivity of High Resolution Positron Emission Tomography Phys. in Med. and Biol. 2007  52    3753-3772 
Graves EE, Giaccia AJ  Imaging Tumoral Hypoxia: Oxygen Concentrations and Beyond Oncology 2007  21  368-378 
Graves EE, Quon A, Loo BW  RT_Image: An Open Source Tool for Investigating PET in Radiation Oncology Technology in Cancer Research and Treatment 2007  111-121 
Graves EE, Quon A, Loo BW  RT_Image: An Open Source Tool for Investigating PET in Radiation Oncology Technology in Cancer Research and Treatment 2007  111-121 
Cecic I, Chan DA, Sutphin PD, Ray P, Gambhir SS, Giaccia AJ, Graves EE  Oxygen sensitivity of reporter genes: implications for preclinical imaging of tumor hypoxia Journal of Molecular Imaging 2007  219-228 
Cecic I, Chan DA, Sutphin PD, Ray P, Gambhir SS, Giaccia AJ, Graves EE  Oxygen sensitivity of reporter genes: implications for preclinical imaging of tumor hypoxia Journal of Molecular Imaging 2007  219-228 
Wu Z, Li Z-B, Chen K, Cai W, He L, Chin FT, Li F, Chen X  microPET Imaging of Tumor Integrin alpha(v)beta(3) Expression Using 18F-labeled PEGylated Tetrameric RGD Peptide (18F-FPRGD4) J Nucl Med 2007  48  1536-1544 
Loening AM, Fenn TD, Gambhir SS  Crystal structures of the luciferase and green Fluorescent protein from Renilla reniformis J. Mol. Biol. 2007  374  1017-1028 
De A, Loening AM, Gambhir SS  An improved bioluminescence resonance energy transfer strategy for imaging intracellular events in single cells and living subjects Cancer Research 2007  67  15  7175-7183 
Loening AM, Wu AM, Gambhir SS  Red-shifted Renilla reniformis luciferase variants for imaging in living subjects Nature Methods 2007  641-643 
Lutz AM, Ray P, Willmann JK, Drescher C, Gambhir SS  2-Deoxy-2-[F-18]fluoro-D-glucose-accumulation in ovarian carcinoma cell lines Molecular Imaging and Biology 2007  260-266 
Biswal S, Resnick DL, Hoffman JM, Gambhir SS   Molecular Imaging: Integration of Molecular Imaging into the Musculoskeletal Imaging Practice. Radiology 2007  244  651-671 
Biswal S, Resnick DL, Hoffman JM, Gambhir SS.   Molecular Imaging: Integration of Molecular Imaging into the Musculoskeletal Imaging Practice. Radiology 2007  244  651-71 
Zilber S, Epstein NJ, Lee SW, Larsen M, Ma T, Smith RL, Biswal S, Goodman SB.  Mouse femoral intramedullary injection model: Technique and microCT scan validation. J Biomed Mater Res B Appl Biomater. 2007  84  286-90 
Fredericson M, Moore W, Biswal S.  Sacral stress fractures: magnetic resonance imaging not always definitive for early stage injuries: a report of 2 cases. Am J Sports Med. 2007  35  835-9 
Li ZJ, Wu JC, Sheikh AY, Kraft D, Cao F, Xie XY, Patel M, Gambhir SS, Robbins RC, Cooke JP, Wu JC  Differentiation, Survival, and Function of Embryonic Stem Cell-Derived Endothelial Cells for Ischemic Heart Disease Circulation 2007  116    I-46–I-54 
Smith FJD, Hickerson RP, Sayers JM, Reeves RE, Contag CH, Leake D, Kaspar RL, McLean WHI   Development of Therapeutic SiRNAs for Pachyonychia Congenita J. Invest. Dermatol. 2007      in press 
Li ZB, Wu Z, Chen K, Chin FT, Chen X.  Click Chemistry for 18F-Labeling of RGD Peptides Bioconjugate Chemistry 2007  18    1987-1994 
Chin FT, Namavari M, Levi J, Subbarayan M, Ray P, Chen X, and Gambhir SS   Semi-automated Radiosynthesis and Biological Evaluation of [18F]FEAU: A Novel PET Imaging Agent for HSV1-tk/sr39tk Reporter Gene Expression Molecular Imaging & Biology 2008  10  82-91 
Chin FT, Namavari M, Levi J, Subbarayan M, Ray P, Chen X, and Gambhir SS   Semi-automated Radiosynthesis and Biological Evaluation of [18F]FEAU: A Novel PET Imaging Agent for HSV1-tk/sr39tk Reporter Gene Expression Molecular Imaging & Biology 2008  10  82-91 
Chan, C.T. and Gambhir, S.S.  Encyclopedia of Diagnostic Imaging Baert (Ed.) Springer, Berlin New York Heidelberg 2008  Accepted     
Chan, C.T., Paulmurugan, R., Gheysens, O.S., Kim J., Chiosis, G., and Gambhir, S.S  Molecular Imaging of The Efficacy of Heat Shock Protein 90 Inhibitors in Living Subjects Cancer Research 2008  68  1-11 
Li Z-B, Wu Z, Cao Q, Dick WD, Tseng RJ, Gambhir SS, Chen X.  Brain Tumor Imaging with 18F-2-Fluorodeoxysorbitol (18F-FDS) Mol Imaging Biol 2007  Dec 21    Epub 
Deroose CM, De A, Loening AM, Chow PL, Ray P, Chatziioannou AF, Gambhir SS  Multimodality Imaging of Tumor Xenografts and Metastasis in Mice with Combined Micro Positron Emission Tomography, Small Animal Computed Tomography and Bioluminescence Imaging JNM 2007  48:  295-303 
Quon A, Chang ST, Chin F, Kamaya A, Dick DW, Loo Jr BW, Gambhir SS, and Koong AC  Initial evaluation of 18F-fluorothymidine (FLT) PET/CT scanning for primary pancreatic cancer Eur. J. Nucl. Med. Mol. Imaging 2008  35  527-31 
Quon A, Chang ST, Chin F, Kamaya A, Dick DW, Loo Jr BW, Gambhir SS, and Koong AC  Initial evaluation of 18F-fluorothymidine (FLT) PET/CT scanning for primary pancreatic cancer Eur. J. Nucl. Med. Mol. Imaging 2008  35  527-31 
Li Z-B, Wu Z, Chen K, Ryu EK, Chen X  18F-Labeled BBN-RGD Heterodimer for Prostate Cancer Imaging J Nucl Med 2008  49  453-61 
Cai W, Hsu AR, Li ZB, Chen X  Are quantum dots ready for in vivo imaging in human subjects? Nanoscale Research Letters 2007    265-281 
Cai W, Ebrahimnejad A, Chen K, Cao Q, Li ZB, Tice DA, Chen X  Quantitative radioimmunoPET imaging of EphA2 in tumor-bearing mice Eur. J. Nucl. Med. Mol. Imaging 2007  34  12  2024-2036 
Cai W, Chen X  Nanoplatforms for targeted molecular imaging in living subjects Small 2007    1840-1854 
Cai W, Niu G, Chen X  Multimodality imaging of the HER-kinase axis in cancer Eur. J. Nucl. Med. Mol. Imaging 2008  35  186-208 
Wang H, Cai W, Chen K, Li ZB, Kashefi A, He L, Chen X  A new PET tracer specific for vascular endothelial growth factor receptor 2 Eur. J. Nucl. Med. Mol. Imaging 2007  34  12  2001-2010 
Cai W, Chen K, Li ZB, Gambhir SS, Chen X  Dual-function probe for PET and near-infrared fluorescence imaging of tumor vasculature J. Nucl. Med. 2007  48    1862-1870 
Cai W, Chen K, Li ZB, Gambhir SS, Chen X  Dual-function probe for PET and near-infrared fluorescence imaging of tumor vasculature J. Nucl. Med. 2007  48    1862-1870 
Veeravagu A, Liu Z, Niu G, Chen K, Jia B, Cai W, Connolly AJ, Tse V, Wang F, Chen X.   Integrin-αvβ3 Targeted Radioimmunotherapy of Glioblastoma Multiforme Clin Cancer Res 2008  14    7330-7339 
Cai W, Chen X  Preparation of peptide conjugated quantum dots for tumour vasculature targeted imaging Nature Protocols 2008  89-96 
Cai W, Chen X  Multimodality molecular imaging of tumor angiogenesis J. Nucl. Med. 2008      in press 
Li Z-B, Chen K, Chen X.  68Ga-labeled Multimeric RGD Peptides for microPET Imaging of Integrin (alpha)v(beta)3 Expression Eur J Nucl Med Mol Imaging 2008  35  1100-8 
Cai W, Hsu AR, Li Z, and Chen X  Are Quantum Dots Ready for In Vivo Imaging in Human Subjects? Nanoscale Research Letters 2007  265-281 
Lau FWY, Olcott PD, Horowitz MA, Peng H, Levin CS  Noise analysis of LSO-PSAPD PET detector front-end multiplexing circuits IEEE Nuclear Science Symposium and Medical Imaging Conference Record 2007    3212-3219 
Foudray A and Levin CS  Bayesian Estimator for Angle Recovery: Event Classification and Reconstruction in Positron Emission Tomography J. of Bayesian Inference and Maximum Entropy Methods 2007      accepted 
Levin CS  New Imaging Technologies to Enhance the Molecular Sensitivity of Positron Emission Tomography Proceedings of the IEEE 2007      accepted 
Habte F, Olcott PD, Levin CS  High Resolution, Light Multiplexed 3D Positioning Scintillation Detector for High Resolution PET IEEE Transactions on Nuclear Science 2007      submitted 
Habte F, Pratx G, Olcott PD, Levin CS  New Geometry for a Whole Body PET System IEEE Transactions on Nuclear Science 2007      submitted 
Levin CS, Zaidi H  Current Trends in Pre-Clinical Positron Emission Tomography System Design PET Clinics 2007      accepted 
Dragulescu-Andrasi A, Rao JH  Chemical labeling of protein in living cells ChemBioChem 2007  10  1099-1101 
Rao J, Dragulescu-Andrasi A, Yao H  Fluorescence imaging in vivo: recent advances Curr. Opin. Biotech 2007  18  17-15 
Lee SW, Greve JM, Leaffer D, Lollini L, Bailey P, Gold GE, Biswal S.  Early findings of small-animal MRI and small-animal computed tomography correlate with histological changes in a rat model of rheumatoid arthritis. NMR Biomed 2007  Nov 20  Epub ahead of print   
de la Zerda A, Gambhir SS  Drug delivery: Keeping tabs on nanocarriers Nature Nanotechnology 2007  12  745-746 
Hsu AR and Chen X  Advances in Anatomic, Functional, and Molecular Imaging of Angiogenesis Journal of Nuclear Medicine 2008  49  511-514 
Lau FWY, Olcott PD, Levin CS  Data acquisition system design for a 1mm^3 resolution PSAPD-based PET system presented at the Joint Molecular Imaging Conference, Providence, Rhode Island, U.S.A. 2007       
Chinn G, Levin CS  PET image reconstruction with a Bayesian projector for multi-electronic collimation schemes 2007 IEEE Nuc. Sci. Symp. Conf. Rec 2007      2799-2802 
Pratx G, Chinn G, Habte F, Olcott PD, Levin CS  Acceleration of Fully 3-D List-Mode OSEM with System Modeling for High-Resolution PET using Graphics Processing Units International Meeting on Fully 3-D Image Reconstruction in Radiology and Nuclear Medicine - Conference Record 2007       
Pratx G, Levin CS  Accurately Positioning Events in a High-Resolution PET System That Uses 3D CZT Detectors IEEE Nuclear Science Symposium and Medical Imaging Conference Record 2007       
Pratx G, Chinn G, Olcott PD, Levin CS  Fully 3D List-Mode OSEM on PC Graphics Hardware: Quantitative Studies IEEE Nuclear Science Symposium and Medical Imaging Conference Record 2007       
Cao Q, Li Z-B, Chen K, Wu Z, He L, Neamati N, Chen X.  Evaluation of Biodistribution and Anti-tumor Effect of a Dimeric RGD Peptide-paclitaxel Conjugate in Mice with Breast Cancer Eur J Nucl Med Mol Imaging 2008  35  1489-1498 
Cai W, Guzman R, Hsu AR, Wang H, Chen K, Sun G, Gera A, Choi R, Bliss T, He L, Li Z, Maag AD, Hori N, Zhao H, Moseley M, Steinberg GK, and Chen X  Positron Emission Tomography Imaging of Post-Stroke Angiogenesis Stroke 2009  40  270-277 
Namavari M, De Jesus OP, Cheng Z, De A, Kovacs E, Levi J, Zhang R, Joshua K. Hoerner JK, Grade H, Syud FA and Gambhir SS  Direct Site-Specific Radiolabeling of an Affibody Protein with 4-[18F]Fluorobenzaldehyde via Oxime Chemistry Mol Imaging Biol 2008  10  177-81 
Cheng Z, Padilla De Jesus O, Namavari M, De A, Levi J, Webster JM, Zhang R, Lee B, Syud FA, Gambhir SS.   Small-Animal PET Imaging of Human Epidermal Growth Factor Receptor Type 2 Expression with Site-Specific 18F-Labeled Protein Scaffold J Nucl Med 2008  49  in press 
Cheng Z, Jelena J  The Application of Cleavable Linker in Development of Molecular Probe for Cancer Molecular Imaging "Recent Advances of Bioconjugate Chemistry in Molecular Imaging" Research Signpost 2008      in press 
Veeravagu A, Liu Z, Niu G, Chen K, Jia B, Cai W, Jin C, Hsu AR, Connolly AJ, Tse V, Wang F, and Chen X   Integrin-alpha(v)beta(3) Targeted Radioimmunotherapy of Glioblastoma Clinical Cancer Research 2008  14  22  7330-7339 
Xie J, Chen K, Lee HY, Xu C, Hsu AR, Peng S, Chen X, and Sun S  Ultra-Small c(RGDyK)-Fe3O4 Nanoparticles and Their Specific Targeting to Integrin αvβ3-rich Tumor Cells Journal of the American Chemical Society 2008  130  24  7542-7543 
Lee H-Y, Lee S-H, Xu C, Xie J, Lee J-H, Wu B, Koh AL, Wang X, Sinclair R, Wang SX, Nishimura DG, Biswal S, Sun S, Cho SH and Chen X  Synthesis and characterization of PVP-coated large core iron oxide nanoparticles as MRI contrast agent. Nanotechnology 2008  Epub ahead of print   
Nguyen JT, Peterson JS, Biswal S, Beaulieu CF and Fredericson M.  Stress-Related Injuries about the Lesser Trochanter in Long-Distance Runners. AJR 2008  in press     
Wang H  Trafficking Mesenchymal Stem Cell Engraftment and Differentiation in Tumor-Bearing Mice by Bioluminescence Imaging Stem Cells 2009       
Wang H  Trafficking Mesenchymal Stem Cell Engraftment and Differentiation in Tumor-Bearing Mice by Bioluminescence Imaging Stem Cells 2009       
De A Yaghoubi SS Gambhir SS  Applications of lentiviral vectors in noninvasive molecular imaging Gene therapy Protocols: Production and in vivo applications of gene transfer vectors. 3rd edition. In: Methods in Molecular Biology 2008    177-202 
Li ZB, Niu G, Wang H, He L, Yang L, Ploug M, Chen X.  Imaging of urokinase-type plasminogen activator receptor expression using a 64Cu-labeled linear peptide antagonist by microPET. Clin Cancer Res 2008  14  15  4758-66 
Willmann JK, Paulmurugan R, Chen K, Gheysens O, Rodriguez-Porcel M, Lutz AM, Chen IY, Chen X, Gambhir SS  US imaging of tumor angiogenesis with microbubbles targeted to vascular endothelial growth factor receptor type 2 in mice Radiology 2008  246  508-18 
Chan CT, Paulmurugan R, ReevesRE, Solow-Cordero D, and Gambhir SS  Molecular Imaging of Phosphorylation Events for Drug Development Molecular Imaging and Biology 2009  11  144-58 
Creusot RJ, Yaghoubi SS, Kodama K, Dang DN, Dang VH, Breckpot K, Thielmans K, Gambhir SS, Fathman CG  Tissue-targeted Therapy of Autoimmune Diabetes Using Dendritic Cells Transduced to Express IL-4 in NOD Mice. Clinical Immunology 2008  127  176-187 
Tseng JR, Kang KW, Dandekar M, Yaghoubi S, Lee JH, Christensen JG, Muir S, Vincent PW, Michaud NR, Gambhir SS  Preclinical Efficacy of the c-Met Inhibitor CE-355621 in a U87 MG Mouse Xenograft Model Evaluated by 18F-FDG Small-Animal PET Journal of Nuclear Medicine 2008  49  129-134 
Yaghoubi SS, Creusot RJ, Ray P, Fathman CG, Gambhir SS  Multimodality Imaging of T Cell Hybridoma Trafficking in Collagen Induced Arthritic Mice: Image Based Estimation of the Number of Cells Accumulating in the Mouse Paws Journal of Biomedical Optics 2007  12  064025_1-11 
Yaghoubi SS and Gambhir SS  Imaging and Cancer The Molecular Basis of Cancer, 3rd ed 2008  Chapter 23    309 
Yaghoubi SS and Gambhir SS  PET imaging of herpes simplex virus type 1 thymidine kinase (HSV1-tk) or mutant HSV1-sr39tk reporter gene expression in mice and humans using [18F]FHBG Nature Protocols 2007  3069-3075 
Lee, H.Y.; Lee, S.H.; Xu, C. J.; Xie, J.; Lee, J. H.; Wu, B.; Koh, A. L.; Wang, X. Y.; Sinclair, R.; Wang, S. X.; Nishimura, D. G.; Biswal S.; Sun S. H.; Cho S. H.; Chen, X. Y.  Synthesis and characterization of PVP-coated large core iron oxide nanoparticles as an MRI contrast agent Nanotechnology 2008  19    165101 
Lee, H.Y.; Lee, S.H.; Xu, C. J.; Xie, J.; Lee, J. H.; Wu, B.; Koh, A. L.; Wang, X. Y.; Sinclair, R.; Wang, S. X.; Nishimura, D. G.; Biswal S.; Sun S. H.; Cho S. H.; Chen, X. Y.  Synthesis and characterization of PVP-coated large core iron oxide nanoparticles as an MRI contrast agent Nanotechnology 2008  19    165101 
Lee, H. Y.; Li Z. B.; Chen K; Hsu A.R.; Xu, C. J.; Xie, J.; Sun, S. H.; Chen, X. Y.  PET/MRI Dual-Modality Tumor Imaging Using Arginine-Glycine-Aspartic (RGD)-Conjugated Radiolabeled Iron Oxide Nanoparticles Journal of Nuclear Medicine 2008  49  1371-1379 
Chen IY, Greve JM, Gheysens O, Willmann JK, Rodriguez-Porcel M, Chu P, Sheikh AY, Faranesh AZ,Paulmurugan R, Yang PC, Wu JC, Gambhir SS  Comparison of optical bioluminescence reporter gene and superparamagnetic iron oxide MR contrast agent as cell markers for noninvasive imaging of cardiac cell transplantation Mol Imaging Biol 2008    Epub ahead of print   
Wang H, Chen K, Niu G, Chen X  Site-Specifically Biotinylated VEGF(121) for Near-Infrared Fluorescence Imaging of Tumor Angiogenesis Mol Pharm 2009  285-94 
de la Zerda A, Zavaleta C, Keren S, Vaithilingam S, Bodapati S, Liu Z, Levi J, Smith BR, Ma T, Oralkan O, Cheng Z, Chen X, Dai H, Khuri-Yakub BT, Gambhir SS  Carbon Nanotubes as Photoacoustic Molecular Imaging Agents in Living Mice Nature Nanotechnology 2008  557-62 
de la Zerda A, Zavaleta C, Keren S, Vaithilingam S, Bodapati S, Liu Z, Levi J, Smith BR, Ma T, Oralkan O, Cheng Z, Chen X, Dai H, Khuri-Yakub BT, Gambhir SS  Carbon Nanotubes as Photoacoustic Molecular Imaging Agents in Living Mice Nature Nanotechnology 2008  557-62 
Chen IY, Greve JM, Gheysens O, Willmann JK, Rodriguez-Porcel M, Chu P, Sheikh AY, Faranesh AZ, Paulmurugan R, Yang PC, Wu JC, Gambhir SS  Comparison of optical bioluminescence reporter gene and superparamagnetic iron oxide MR contrast agent as cell markers for noninvasive imaging of cardiac cell transplantation Mol Imaging Biol 2009  11  178-87 
Jacobson, G.B Shinde, R Contag, C.H. Zare, R.N.  Sustained Release of Drugs Dispersed in POlymer Nanoparticles Angewandte Chemie International Edition 2008  47     
Gowrishankar G, Rao J  Visualizing RNA splicing in vivo Molecular Biosystems 2007  301-7 
Gowrishankar G and Rao J  Visualizing RNA splicing in vivo Molecular Biosystems 2007  301-7 
Yerushalmi D, Quon A, Fahrig R, Pelc NJ, Fann JI, Gambhir SS  PET-CT Fly-through Virtual Bronchoscopy – Lesion Quantification & Parameters Affecting 3D Visualization Academy of Molecular Imaging 2007    Abstract   
Yerushalmi D, Quon A, Fahrig R, Pelc NJ, Fann JI, Gambhir SS  PET-CT Fly-through Virtual Bronchoscopy – Lesion Quantification & Parameters Affecting 3D Visualization Academy of Molecular Imaging 2007    Abstract   
Cao F*, Wagner RA*, Wilson KD*, Xie X, Fu J, Drukker M, Lee A, Li RA, Gambhir SS, Weissman IL, Robbins RC, Wu JC   Transcriptional and functional profiling of human embryonic stem cell-derived cardiomyocytes PLoS ONE 2008  10  e3474 
Zavaleta, C., de la Zerda, A., Liu, Z., Keren, S., Cheng, Z., Schipper, M., Chen, X., Dai, H. & Gambhir, S.S.   Noninvasive Raman spectroscopy in living mice for evaluation of tumor targeting with carbon nanotubes. Nano Letters 2008    2800-5 
Zavaleta, C., de la Zerda, A., Liu, Z., Keren, S., Cheng, Z., Schipper, M., Chen, X., Dai, H. & Gambhir, S.S.   Noninvasive Raman spectroscopy in living mice for evaluation of tumor targeting with carbon nanotubes. Nano Letters 2008    2800-5 
Yang C-T, Kim Y-S, Wang J, Wang L, Shi J, Li Z-B, Chen X, Fan M, Li J-J, Liu S  64Cu-Labeled 2-(Diphenylphosphoryl)ethylphenylphosphonium Cations as Highly Selective Tumor Imaging Agents: Effects of Linkers and 64Cu Chelates on Biodistribution Characteristics Bioconjugate Chemistry 2008      Sep 3. [Epub ahead of print] 
Niu G, Chen X  Has Molecular and Cellular Imaging Enhanced Drug Discovery? Drugs in R&D 2008  351-368 
Wang H, Chen X  Imaging Mesenchymal Stem Cell Migration and the Implications for Stem Cell – Based Cancer Therapies Future Oncology 2008  623-628 
Chen K, Li Z-B, Wang H, Cai W, Chen X  Modification of Quantum Dot for Dual Modality Imaging of Tumor Vascular VEGFR. Eur J Nucl Med Mol Imaging 2008  35  12  2235-44 
Cai W, Niu G, Chen X  Imaging of Integrins as Biomarkers for Tumor Angiogenesis Curr Pharm Des 2008  14  28  2943-2971 
Xie J, Chen K, Lee H-Y, Xu C, Hsu AR, Peng S, Chen X*, Sun S  Ultra-Small c(RGDyK)-Fe3O4 Nanoparticles and Their Specific Targeting to Integrin αvβ3-rich Tumor Cells J Am Chem Soc 2008  130  24  7542-7543 
Shi J, Jia B, Liu Z, Yang Z, Yu Z, Chen K, Chen X, Liu S, Wang F  99mTc-Labeled Bombesin(7-14)NH2 with Favorable Properties for SPECT Imaging of Colon Cancer Bioconjug Chem 2008  19  1170-1178 
Chen K, Cai W, Li Z-B, Wang H, Chen X  Quantitative PET imaging of VEGF receptor expression Mol Imaging Biol 2008  11  15-22 
Huang M, Chan D, Jia F, Xie X, Li Z, Hoyt G, Robbins RC, Chen X, Giaccia A, Wu JC  Molecular Imaging of RNA Interference Therapy Targeting Prolyl Hydroxylase-2 for Treatment of Myocardial Ischemia Circulation 2008  118  14 Suppl  S226-S233 
Cao Q, Cai W, Niu G, He L, Chen X  Multimodality Imaging of IL-18bp-Fc Therapy of Experimental Lung Metastasis Clin Cancer Res 2008  14  19  6137-6145 
Kim Y-S, Yang C-T, Wang J, Wang L, Li Z-B, Chen X, Liu S  Effects of Targeting Moiety, Linker, Bifunctional Chelator and Molecular Charge on Biological Properties of 64Cu-Labeled Triphenylphosphonium Cations J Med Chem 2008  51  10  2971-2984 
Ryu EK, Wu Z, Chen K, Lazarus LH, Markzak E, Sasaki Y, Ambo A, Salvadori S, Ren C, Zhao H, Balboni G, Chen X  Synthesis and Evaluation of a Potent and Selective 18F-Labeled δ-Opioid Receptor Antagonist J Med Chem 2008  51  1817-1823 
Alam MR, Dixiti V, Kang H, Li Z-B, Chen X, Juliano R  Intracellular Delivery of an Anionic Antisense Oligonucleotide via Receptor Mediated Endocytosis. Nucl Acid Res 2008  36  2764-2776 
Wang H, Chen K, Cai W, Li Z, He L, Kashefi A, Chen X  Integrin Targeted Imaging and Therapy with RGD4C-TNF Fusion Protein Mol Cancer Ther 2008  1044-1053 
So MK, Gowrishankar G,Hasegawa S,Chung JK and Rao J  Imaging Target mRNA and siRNA-Mediated Gene Silencing In Vivo with Ribozyme-Based Reporters ChemBiochem 2008  16  2682-2691 
Liu Z, Yan Y, Chin FT, Wang F, and Chen X  Dual Integrin and Gastrin-Releasing Peptide Receptor Targeted Tumor Imaging Using 18F-labeled PEGylated RGD-Bombesin Heterodimer 18F-FB-PEG3-Glu-RGD-BBN J. Med. Chem 2009  52  425-432 
Liu Z, Yan Y, Chin FT, Wang F, and Chen X  Dual Integrin and Gastrin-Releasing Peptide Receptor Targeted Tumor Imaging Using 18F-labeled PEGylated RGD-Bombesin Heterodimer 18F-FB-PEG3-Glu-RGD-BBN J. Med. Chem 2009  52  425-432 
Liu Z, Yan Y, Chin FT, Wang F, and Chen X  Dual Integrin and Gastrin-Releasing Peptide Receptor Targeted Tumor Imaging Using 18F-labeled PEGylated RGD-Bombesin Heterodimer 18F-FB-PEG3-Glu-RGD-BBN J. Med. Chem 2009  52  425-432 
Liu Z, Yan Y, Chin FT, Wang F, and Chen X  Dual Integrin and Gastrin-Releasing Peptide Receptor Targeted Tumor Imaging Using 18F-labeled PEGylated RGD-Bombesin Heterodimer 18F-FB-PEG3-Glu-RGD-BBN J. Med. Chem 2009  52  425-432 
Namavari M, Cheng Z, Zhang R, De A, Levi J, Hoerner JK, Yaghoubi SS, Syud FA, and Gambhir SS  A Novel method for Direct site-specific Radiolabeling of peptides Using [18F]FDG Bioconjug Chem 2009  20    432-436 
Lee S and Chen X  Dual-Modality Probes for In Vivo Molecular Imaging Molecular Imaging 2009   
F. W. Y. Lau, A. Vandenbroucke, P. D. Reynolds, P. D. Olcott, M. A. Horowitz, C. S. Levin  Front-end electronics for a 1mm^3 resolution avalanche photodiode-based PET System with analog signal multiplexing IEEE Nuclear Science Symposium and Medical Imaging Conference Record 2008      3871-3874 
F. W. Y. Lau, C. Fang, P. D. Reynolds, P. D. Olcott, A. Vandenbroucke, V. C. Spanoudaki, F. Olutade, M. A. Horowitz, C. S. Levin  1mm^3 resolution breast-dedicated PET system IEEE Nuclear Science Symposium and Medical Imaging Conference Record 2008      5619-5622 
P. D. Olcott, F. W. Y. Lau, C. S. Levin  Data acquisition system design for a 1mm^3 resolution PSAPD-based PET system IEEE Nuclear Science Symposium and Medical Imaging Conference Record 2007    3206-3211 
A. Vandenbroucke, A. M. K. Foudray, F. W. Y. Lau, P. D. Olcott, P. D. Reynolds, C. S. Levin  IEEE Nuclear Science Symposium and Medical Imaging Conference Record Performance characterization of a new high resolution PET scintillation detector 2008      3604-3608 
Kimura RH, Cheng Z, Gambhir SS, Cochran JR  Engineered knottin peptides: a new class of agents for imaging integrin expression in living subjects Cancer Res 2009  69  2435-42 
Webster JM, Zhang R, Gambhir SS, Cheng Z*, Syud FA*  Engineered Two-Helix Small Proteins for Molecular Recognition ChemBioChem 2009  10    1293-1296 
Hara W, Loo BW Jr, Goffinet DR, Chang SD, Adler JR, Pinto HA, Fee WE, Kaplan MJ, Fischbein NJ, Le QT  Excellent local control with stereotactic radiotherapy boost after external beam radiotherapy in patients with nasopharyngeal carcinoma Int J Radiat Oncol Biol Phys 2008  71  393-400 
Lee P, Weerasuriya DK, Lavori PW, Quon A, Hara W, Maxim PG, Le QT, Wakelee HA, Donington JS, Graves EE, Loo BW Jr  Metabolic tumor burden predicts for disease progression and death in lung cancer Int J Radiat Oncol Biol Phys 2007  69  328-33 
Lee P, Weerasuriya DK, Lavori PW, Quon A, Hara W, Maxim PG, Le QT, Wakelee HA, Donington JS, Graves EE, Loo BW Jr  Metabolic tumor burden predicts for disease progression and death in lung cancer Int J Radiat Oncol Biol Phys 2007  69  328-33 
Maxim PG, Loo BW Jr, Shirazi H, Thorndyke B, Luxton G, Le QT  Quantification of motion of different thoracic locations using four-dimensional computed tomography: implications for radiotherapy planning Int J Radiat Oncol Biol Phys 2007  69  1395-401 
Patel DA, Chang ST, Goodman KA, Quon A, Thorndyke B, Gambhir SS, McMillan A, Loo BW Jr, Koong AC  Impact of integrated PET/CT on variability of target volume delineation in rectal cancer Technol Cancer Res Treat 2007  31-6 
Patel DA, Chang ST, Goodman KA, Quon A, Thorndyke B, Gambhir SS, McMillan A, Loo BW Jr, Koong AC  Impact of integrated PET/CT on variability of target volume delineation in rectal cancer Technol Cancer Res Treat 2007  31-6 
Quon A, Fischbein NJ, McDougall IR, Le QT, Loo BW Jr, Pinto H, Kaplan MJ  Clinical role of 18F-FDG PET/CT in the management of squamous cell carcinoma of the head and neck and thyroid carcinoma J Nucl Med 2007  48  Supp 1  58S-67S 
Kothary N, Heit JJ, Louie JD, Kuo WT, Loo BW Jr, Koong A, Chang DT, Hovsepian D, Sze DY, Hofmann LV  Safety and efficacy of percutaneous fiducial marker implantation for image-guided radiation therapy J Vasc Interv Radiol 2009  20  235-9 
Yamamoto T, Langner U, Loo BW Jr, Shen J, Keall PJ  Retrospective analysis of artifacts in four-dimensional CT images of 50 abdominal and thoracic radiotherapy patients Int J Radiat Oncol Biol Phys 2008  72  1250-8 
Padda S, Kothary N, Donington J, Cannon W, Loo BW Jr, Kee S, Wakelee H  Complications of ablative therapies in lung cancer Clin Lung Cancer 2008  122-6 
La TH, Filion EJ, Turnbull BB, Chu JN, Lee P, Nguyen K, Maxim P, Quon A, Graves EE, Loo BW Jr, Le QT  Metabolic Tumor Volume Predicts for Recurrence and Death in Head-and-Neck Cancer Int J Radiat Oncol Biol Phys 2009      in press 
La TH, Filion EJ, Turnbull BB, Chu JN, Lee P, Nguyen K, Maxim P, Quon A, Graves EE, Loo BW Jr, Le QT  Metabolic Tumor Volume Predicts for Recurrence and Death in Head-and-Neck Cancer Int J Radiat Oncol Biol Phys 2009      in press 
Yerushalmi D, Mullick R, Quon A, Fahrig R, Pelc NJ, Fann JI, Gambhir SS  Simulations of Virtual PET-CT 3D Bronchoscopy Imaging Using a Physical Porcine Lung-Heart Phantom Molecular Imaging and Biology 2009    (in press)   
Yerushalmi D, Mullick R, Quon A, Fahrig R, Pelc NJ, Fann JI, Gambhir SS  Simulations of Virtual PET-CT 3D Bronchoscopy Imaging Using a Physical Porcine Lung-Heart Phantom Molecular Imaging and Biology 2009    (in press)   
Willmann JK, Paulmurugan R, Rodriguez-Porcel M, Stein W, Brinton TJ, Connolly AJ, Nielsen CH, Lutz AM, Lyons J, Ikeno F, Suzuki Y, Rosenberg J, Chen IY, Wu JC, Yeung AC, Yock P, Robbins RC, Gambhir SS  Imaging gene expression in human mesenchymal stem cells: from small to large animals Radiology 2009  252  117-27 
Cheng Z, De Jesus OP, Kramer DJ, De A, Webster JM, Gheysens O, Levi J, Namavari M, Wang S, Park JM, Zhang R, Liu H, Lee B, Syud FA, Gambhir SS  64Cu-Labeled Affibody Molecules for Imaging of HER2 Expressing Tumors Mol Imaging Biol 2009  Sep 25. [Epub ahead of print]     
Chen K, Xie J, Xu H, Behera D, H Michalski M, Biswal S, Wang A, Chen X  Triblock copolymer coated iron oxide nanoparticle conjugate for tumor integrin targeting. Biomaterials 2009       
Chen K, Xie J, Xu H, Behera D, H Michalski M, Biswal S, Wang A, Chen X  Triblock copolymer coated iron oxide nanoparticle conjugate for tumor integrin targeting. Biomaterials 2009       
Ren G, Miao Z, Liu HG, Jiang L, Limpa-Amara N, Mahmood A, Gambhir SS, Cheng Z.  Melanin-Targeted Preclinical PET Imaging of Melanoma Metastasis Journal of Nuclear Medicine 2009  50  10  1692-9 
D'Souza AL, Tseng JR, Butts Pauly K, Guccione S, Rosenberg J, Gambhir SS, Glazer GM  A strategy for blood biomarker amplification and localization using ultrasound PNAS 2009  106  40  17152-17157 
Levi J, Cheng Z, Gheysens O, Patel M, Chan CT, Wang Y, Namavari M, Gambhir SS.  Fluorescent fructose derivatives for imaging breast cancer cells. Bioconjugate Chemistry 2007  18  628-34 
Levi J, De A, Cheng Z, Gambhir SS  Bisdeoxycoelenterazine derivatives for improvement of bioluminescence resonance energy transfer assays J Am Chem Soc 2007  129  39  11900-1 
Levi J, De A, Cheng Z, Gambhir SS.  Bisdeoxycoelenterazine derivatives for improvement of bioluminescence resonance energy transfer assays J Am Chem Soc 2007  129  39  11900-1 
Levi J, De A, Cheng Z, Gambhir SS.  Bisdeoxycoelenterazine derivatives for improvement of bioluminescence resonance energy transfer assays J Am Chem Soc 2007  129  39  11900-1 
Namavari M, Padilla De Jesus O, Cheng Z, De A, Kovacs E, Levi J, Zhang R, Hoerner JK, Grade H, Syud FA, Gambhir SS  Direct site-specific radiolabeling of an Affibody protein with 4-[18F]fluorobenzaldehyde via oxime chemistry. Mol Imaging Biol. 2008  10  177-81 
Cheng Z, De Jesus OP, Kramer DJ, De A, Webster JM, Gheysens O, Levi J, Namavari M, Wang S, Park JM, Zhang R, Liu H, Lee B, Syud FA, Gambhir SS.  (64)Cu-Labeled Affibody Molecules for Imaging of HER2 Expressing Tumors Mol Imaging Biol. 2009       
Willmann JK, Chen K, Wang H, Paulmurugan R, Rollins M, Cai W, Wang DS, Chen IY, Gheysens O, Rodriguez-Porcel M, Chen X, Gambhir SS  Monitoring of the biological response to murine hindlimb ischemia with 64Cu-labeled vascular endothelial growth factor-121 positron emission tomography Circulation 2008  117  915-22 
Paulmurugan R, Padmanabhan P, Ahn BC, Ray S, Willmann JK, Massoud TF, Biswal S, Gambhir SS  A novel estrogen reception intramolecular folding based titratable transgene expression system Mol Ther 2009  17    1703-11 
Paulmurugan R, Padmanabhan P, Ahn BC, Ray S, Willmann JK, Massoud TF, Biswal S, Gambhir SS  A novel estrogen reception intramolecular folding based titratable transgene expression system Mol Ther 2009  17    1703-11 
Gaster RS, Hall DA, Nielsen CH, Osterfeld SJ, Yu H, Mach KE, Wilson RJ, Murmann B, Liao JC, Gambhir SS, Wang SX  Matrix-insensitive protein assays push the limits of biosensors in medicine Nature Medicine 2009  15  11  1327-32 



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