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2008 MIPS/GE Medical Systems
Seminar 4:30 − 5:15 pm |
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| Jan. 14, 2008 Clark Auditorium  Harrison H. Barrett, PhD Vice Chair, Rad Regents Prof., Rad Univ. of Arizona View Webcast 
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A unified approach to adaptive and multimodality imaging: Acquisition hardware, statistical theory and objective assessment
Abstract: Multimodality imaging, which provides complementary anatomical and functional information, is very valuable in clinical and biomedical applications. Adaptive imaging, in which a system autonomously alters its configuration or acquisition protocol in response to image information from a particular subject, is in a much earlier stage of development, but it has the potential to provide a further improvement in patient care and biomedical research. This presentation will explore some of the connections between multimodality and adaptive imaging. A common theoretical framework will be presented, relevant statistical issues will be introduced, and recent progress towards implementation of adaptive methods in SPECT and CT will be reviewed. |
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| Jan 28, 2008 | Imaging VEGF Receptor Expression Weibo Cai, Chen Lab |
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| Feb 4, 2008 Clark Auditorium Robin P. Choudhury, MA, DM, MRCP Wellcome Trust Clinical Fellow Oxford University Dept of CV Medicine Hon. Consultant Cardiologist John Radcliffe Hospital Oxford View Webcast
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Microparticles of iron oxide for molecular MRI
Abstract: Micro-particles of iron oxide (MPIO) have been used for cellular imaging and tracking. For some molecular imaging applications the size of these particles would preclude delivery to the site of interest. However, for imaging endovascular targets, MPIO possess several positive attributes. Firstly, MPIO convey a payload of iron that is orders of magnitude greater than ultrasmall particles of iron oxide (USPIO). Secondly, the effects of MPIO on local magnetic field homogeneity, and therefore detectable contrast, extend a distance many times their physical diameter. Thirdly, once bound to endothelium, MPIO remain intravascular thereby allowing bound MPIO to be readily distinguished from the vessel wall. Finally, conjugated MPIO may offer a generic tool for imaging endothelial-specific markers across a range of vascular pathologies. Accordingly, we have adopted a MPIO-based approach for targeted MRI and applied this to the detection of adhesion molecules on the arterial endothelium (atherosclerosis and brain inflammation) and activated platelets (arterial thrombosis and cerebral malaria). |
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| Feb 25, 2008 Alway Bldg., M114 |
Biochemistry by other means: Using imaging to deconstruct T cell recognition Mark Davis, The Burt and Marion Avery Family Professor, Microbiology and Immunology |
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| Mar 3, 2008 | Photoacoustic Molecular Imaging Adam de la Zerda, Gambhir Lab |
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| Mar 10, 2008 | TBD |
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| Mar 17, 2008 Clark Auditorium  Robert Gropler, MD Prof. Rad, Med and Bio Eng, Mallinckrodt Institute of Radiology View Webcast
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Diabetic cardiomyopathy: Use of imaging to cross the translational divide
Abstract: There is a growing epidemic of diabetes mellitus in the United States with a projected increase of 30% in the prevalence of this disease over the next 10 years. Cardiovascular disease is the leading cause of morbidity and mortality in these patients. The myocardial metabolic phenotype of the diabetic heart, an over-dependence on fatty acid metabolism, appears to be an important contributor to the left ventricular dysfunction observed in these patients. Our work has focused on optimizing PET techniques to provide quantitative measurements of myocardial substrate metabolism that are applicable in rodent to human heart. We are then applying these methods to better characterize the metabolic perturbations of the diabetic heart, their contribution to left ventricular dysfunction and the potential role of novel therapeutic approaches to reduce the cardiovascular manifestations of this disease. |
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| Mar 24, 2008 | CANCELLED | ||||
| Mar 31, 2008 | A General Method to Regulate Protein Function in Living Mice Tom Wandless Assistant Professor (Research) of Chemical and Systems Biology and, by courtesy, of Chemistry, Stanford University |
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| Apr 7, 2008 Clark Auditorium  Robert Innis, MD, PhD Chief, Molecular Imaging branch National Institutes of Health View Webcast
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Evaluation of Novel PET Radioligands for Two Targets: 1) P-gp Efflux Transporter and 2) Inflammation
Abstract: NA |
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| Apr 14, 2008 | Noninvasive Molecular Imaging of Small Living Subjects using Raman Spectroscopy Christina Zavaleta, PhD, Gambhir Lab Interventional Gene Delivery/Therapy for Hepatocellular Carcinoma in a Novel Rat Hepatoma Model Abhinav Singh, MD, Gambhir Lab |
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| Apr 21, 2008 | Inflammation and Atherosclerosis: Imaging Macrophages in the Vessel Wall Masahiro Terashima, McConnell Lab |
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| Apr 28, 2008 | Molecular Imaging of Abdominal Aortic Aneurysms Maureen Tedesco and Geoff Schultz (Ronald Dalman Lab., Vasc. Surgery) Med/Cardiovascular Medicine |
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| May 5, 2008 | Nerves on Fire:Imaging Nociception with Manganese-Enhanced MRI (MEMRI) Deepak Behera, PhD, Biswal Lab 3D Conformal Radiation Therapy System for Small Experimental Animals Hu Zhou, PhD, Graves lab |
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| May 12, 2008 Clark Auditorium  Stuart Lindsay, PhD Edward and Nadine Carson Professor of Physics and Chemistry, Biodesign Institute, Arizona State University |
Single Molecule Tools for Genomics
Abstract: Genomic diversity, be it at the DNA level, or at the epigenetic level, is probably an essential part of development. There is therefore a need to develop tools capable of sequencing genomes rapidly and sequentially from even single cells, and for mapping post translational modifications that carry the epigenetic code, once again, from single cells, and with high spatial resolution. We are developing atomic-force microscope based methods for mapping post translational modifications on single proteins with nm-scale resolution, and results will be presented for one type of histone modification. We are also pursuing a novel single molecule approach to DNA sequencing which we call "Sequencing by Recognition". It is based on a self-assembled tunnel junction in which an electronic signal is produced when a hydrogen bonded "sandwich" is formed between an electrode, a backbone phosphate, sugar and base to a second base tethered to a second electrode. |
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| May 19, 2008 | Modeling cancer associated with loss of function of the retinoblatoma tumor suppressor gene Julien Sage Assistant Professor of Pediatrics and of Genetics, Stanford University |
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| May 26, 2008 | Mechanisms of telomerase function in stem cells and cancer Steven Artandi, MD, PhD Assistant Professor of Medicine, Stanford University |
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| June 2, 2008 | Real-time Intravital Imaging of Nanoparticle Behavior in Tumor Neovasculature Bryan Smith, Gambhir Lab |
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| June 9, 2008 Clark Auditorium |
CANCELLED
Abstract: |
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| June 30, 2008 | Single-Biomolecule Optical Imaging, Superresolution, and Trapping W.E. Moerner Harry S. Mosher Professor and Professor, by courtesy, of Applied Physics, Dept. of Chemistry, Stanford Universit |
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| July 7, 2008 | Development of VEGF121-derived probes for imaging angiogenesis Gang Niu, PhD, Chen Lab EGFR imaging with radiolabled antibodies Hui Wang, PhD, Chen Lab |
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| July 14, 2008 Clark Auditorium Dean Sherry, PhD Prof. Chem, Dir., Advanced Imaging Research Center, Univ. of Texas, Southwestern |
TBD
Abstract: TBD |
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| July 21, 2008 | TBD Beverly Mitchell, MD George E. Becker Professor in Medicine and Professor, by courtesy, of Chemical and Systems Biology, Dept. of Medicine Oncology |
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| July 28, 2008 | TBD Geoff Gurtner, MD Associate Professor of Surgery, Stanford University |
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| Aug 4, 2008 | TBD Byunghee Yoo, PhD, Chen Lab TBD Kitch Wilson, Wu Lab |
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| Aug 11, 2008 Clark Auditorium  David Townsend, PhD Prof., Med. & Rad. Dir., Molecular Imaging and Translational Research Program UT Med Center |
Multimodality imaging of structure and function: from design to applications
Abstract: TBD |
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| Aug 18, 2008 | TBD Lei Xing, PhD Associate Professor of Radiation Oncology, Stanford University |
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| Aug 25, 2008 | TBD |
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| Sept 1, 2008 | TBD Hisanori Kosuge, McConnell Lab TBD Noriyuki Miyama, Dalman Lab |
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| Sept 8, 2008 Clark Auditorium  Mark W. Dewhirst, DVM, PhD Gustavo S. Montana Prof, Rad. Onc. Prof., Path & Bio. Eng. Duke University |
TBD
Abstract: TBD |
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| Sept 15, 2008 | TBD Minal Vasanawala, MD, PhD, Nuclear Medicine, VA Palo Alto |
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| Sept 22, 2008 | TBD Gary Nolan, PhD Associate Professor of Microbiology and Immunology, Stanford University |
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| Oct 6, 2008 | TBD Geoffrey Schultz, Dalman Lab TBD Mayumi Yamada, Yang Lab |
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| Oct 13, 2008 Clark Auditorium  Arthur Toga, PhD Dir., Lab of Neuro Imaging UCLA Sch of Med |
Brain mapping the structure and function of mice and men
Abstract: TBD |
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| Oct 20, 2008 | TBD Jennifer Cochran, PhD Assistant Professor of Bioengineering, Stanford University |
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| Oct 27, 2008 | TBD Shreyas Vasanawala, MD, PhD, Assistant Professor of Radiology at the Stanford University Medical Center, Stanford University |
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| Nov 3, 2008 | TBD Hao Peng, PhD, Levin Lab |
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| Nov 10, 2008 Clark Auditorium TBD |
Title: TBD
Abstract: TBD |
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| Nov 17, 2008 | TBD Andrei Iagaru, MD, Nucelar Medicine Clinic |
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| ONov 24, 2008 | TBD Zhen Cheng, MD, Cheng Lab |
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| Dec 1, 2008 | TBD Juergen Willmann, Gambhir Lab TBD Jin Hyung Lee, Nishmura Lab |
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| Dec 8, 2008 Clark Auditorium Robert Simari, MD Mayo Clinic |
Title: TBD
Abstract: TBD |
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| Dec 15, 2008 | An overview of intravascular ultrasound and insights into coronary interventions Paul Yock, The Martha Meier Weiland Professor in the School of Medicine and Professor of Bioengineering and, by courtesy, of Mechanical Engineering and at the GSB |
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Sponsored by: Molecular Imaging Program at Stanford (MIPS) (mips.stanford.edu); Host: Director, Sanjiv Sam Gambhir, MD, PhD (sgambhir@stanford.edu) Supported by: GE Medical Systems (http://www.gehealthcare.com/worldwide.html) Archived Molecular Seminar Series - 2007 | 2006 | 2005 | 2003-2004 If you would like to be included on the MIPS email distribution list for weekly meeting reminders, contact Susan Singh. |
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| Updated July 3, 2008 | |||||
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