Center for Cancer Nanotechnology Excellence Focused on Therapy Response

Faculty

Samir Hanash, M.D., Ph.D. Co-Leader: Project 4 Fred Hutchinson Cancer Research Center Molecular Diagnostic PO BOX 19024 1100 Fairview Ave N, M5-C800 Seattle, WA 98109 Phone: 206-667-5703 Fax: 206-667-2537 Email: shanash@fhcrc.org

Co-Project Leader: Project 4, Professor of Human Biology, (Fred Hutchinson Cancer Research Center)
Dr. Hanash is Director of Molecular Diagnostics and the Fred Hutchinson Cancer Center. His research interests have focused on the global profiling of cancer even before the merits of such an effort were widely recognized. He has also recognized the merits of integrated genomic and proteomic profiling and has been among the very first to integrate the molecular analysis of cancer at the genomic, transcriptomic and proteomic levels, with substantial reliance on array technology. Another important area that he has pioneered is the application of proteomics to the identification of tumor antigens that induce an antibody response in cancer patients. The use of natural tumor protein microarrays has allowed assessment of the antigenic properties of proteins in their natural state as derived from tumors, leading to the isolation of those tumor antigens with the greatest potential to provide a molecular signature for the detection of cancer at an early stage. Dr Hanash has just finished a three-year term as the inaugural president of the Human Proteome Organization.

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