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Marybeth Pysz
Marybeth Pysz
Postdoctoral Fellow, SMIS Program
Primary Mentor: Juergen K. Willmann, M.D.
Secondary Mentor: Sanjiv Sam Gambhir, MD, PhD
Education:PhD, Chemical Engineering, North Carolina State University, Raleigh, NC, 2003
MS, Chemical Engineering, North Carolina State University, Raleigh, NC, 1999
BS, Chemical Engineering, State University of New York at Buffalo, Buffalo, NY, 1997
Awards:12/08 - present SMIS Fellow, Stanford University
7/05 - 7/08 Ruth L. Kirschstein NRSA Postdoctoral Fellowship - NIH F32
Address:Molecular Imaging Program at Stanford
Department of Radiology
Stanford University
1201 Welch Road
Lucas Expansion, P087
Stanford, CA 94305-5484
Phone:(650) 724-1472
Fax:(650) 736-7925
E-mail: mpysz@stanford.edu
Recent Publications:
  • Pysz MA, Leontieva OV, Bateman NW, Uronis JM, Curry KJ, Threadgill DW, Janssen KP, Robine S, Velcich A, Augenlicht LH, Black AR, Black JD.. PKCalpha tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1.. Experimental Cell Research.2009; 315(8): 1415-1428.

  • Guan L, Song K, Pysz MA, Curry KJ, Hizli AA, Danielpour D, Black AR, and Black JD. PKC-mediated down-regulation of cyclin D1 involves activation of the translation repressor 4E-BP1 via a PI3K/Akt-independent, PP2A-dependent mechanism in intestinal epithelial cells. Journal of Biological Chemistry.2007; 282(19): 14213-14225.

  • Hizli AA, Black AR, Pysz MA, and Black JD. Protein kinase C signaling regulates expression of cyclin D1 in IEC-18 cells. Journal of Biological Chemistry.2006; 281(21): 14596-14603.

  • Shockley KR, Scott KL, Pysz MA, Conners SB, Johnson MR, Montero CI, Wolfinger R, and Kelly RM. Genome-wide transcriptional variation within and between steady states for continuous growth of the hyperthermophile Thermotoga maritima. Applied and Environmental Microbiology.2005; 71(9): 5572-5576.

  • Clark JA, Black AR, Leontieva OV, Frey MR, Pysz MA, Kunneva L, Wolozynska-Read A, Roy D, and Black JD. Involvement of the ERK signaling cascade in protein kinase C-mediated cell cycle arrest in intestinal epithelial cells. Journal of Biological Chemistry.2004; 279(10): 9233-9247.

  • Johnson MR, Montero CI, Conners SB, Shockley KR, Pysz MA, and Kelly RM. Functional genomics-based studies of the microbial ecology of hyperthermophilic micro-organisms. Biochemical Society Transactions.2004; 32(Pt 2): 188-192.

  • Pysz MA, Conners SB, Montero CI, Shockley KR, Johnson MR, Ward DE, and Kelly RM. Transcriptional analyses of biofilm formation processes in the anaerobic hyperthermophilic bacterium Thermotoga maritima. Applied and Environmental Microbiology.2004; 70(10): 6098-6112.

  • Pysz MA, Montero CI, Chhabra SR, Rinker KD, and Kelly RM. Significance of polysaccharides in the microbial physiology and ecology of hydrothermal vent environments. “The Subseafloor Biosphere at Mid-Ocean Ridges,” Wilcock WSD, Delong EF, Kelley DS, Baross JA, and Cary SC (Eds.), American Geophysical Union, Washington DC.2004; (): 213-226.

  • Pysz MA, Ward DE, Shockley KR, Montero CI, Conners SB, Johnson MR, and Kelly RM. Transcriptional analysis of dynamic heat shock response by the hyperthermophilic bacterium Thermotoga maritima. Extremophiles.2004; 8(3): 209-217.

  • Gao J, Bauer MW, Shockley KR, Pysz MA, and Kelly RM. Hyperthermophilic archaeon Pyrococcus furiosus growth on chitin involves two family 18 chitinase. Applied and Environmental Microbiology.2003; 69(6): 3119-3128.

  • Burke MD, Ha SY, Pysz MA, and Khan SA. Rheology of protein gels synthesized through a combined enzymatic and heat treatment method. International Journal of Biological Macromolecules.2002; 37(1-3): 37-44.

  • Pysz MA, Rinker KD, Shockley KR, and Kelly RM. Continuous cultivation methods for hyperthermophilic biomass and enzyme production. Methods in Enzymology.2001; 330(A): 31-40.



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