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Zhen Cheng
Zhen Cheng
Assistant Professor, Radiology
Member of Molecular Imaging Program at Stanford, BioX Program, Stanford Cancer Center
and Canary Center at Stanford for Early Cancer Detection
Education:Post-Doc Fellow. Department of Radiology, Harvard Medical School, 2001-2003
Ph.D. Department of Chemistry, University of Missouri-Columbia, 1997-2001
M.S. China Institute of Atomic Energy & National Research Center of Isotope Engineering and Technology, 1994-1997
B.S. Department of Chemistry, Sichuan University, 1990-1994
Awards:Melanoma Research Alliance, Young Investigator Award, 2009
Society of Nuclear Medicine, Pilot Research Grant, 2008
California Breast Cancer Research Program, IDEA Award, 2008
Young Investigator Travel Scholarship, The Academy of Molecular Imaging Annual Conference 2005
Graduate Fellowship, University of Missouri-Columbia, 1997-1998
Address:Molecular Imaging Program at Stanford
Department of Radiology
1201 Welch Road, Lucas Center, P020A
Mail Code 5484
Stanford University
Stanford, CA, 94305-5484
Phone:650-723-7866
Fax:650-736-7925
E-mail: zcheng@stanford.edu
Research Interests:To develop novel molecular imaging probes and techniques for non-invasively early detection of cancer using multimodality imaging technologies including PET, SPECT, MRI, optical imaging, etc.
Current Labs:Cancer Molecular Imaging Chemistry Laboratory (CMICL)
Previous Labs:Multimodality Molecular Imaging Lab
Recent Publications:
  • Gao J, Chen K, Xie R, Xie J, Lee S, Cheng Z, Peng X, Chen X. Ultrasmall Near-Infrared Non-cadmium Quantum Dots for in vivo Tumor Imaging. Small. 2010;6():256-261.

  • Gao, J. H.; Chen, X. Y.; Cheng, Z. Near-infrared Quantum Dots as Optical Probes for Tumor Imaging. Curr. Top. Med. Chem. 2010;():in press.

  • He X, Wang KM, Cheng Z* . In vivo near-infrared fluorescence imaging of cancer with nanoparticles-based probes. WIREs Nanomedicine and Nanobiotechnology. 2010;3(In press):.

  • Jiang L, Kimura RH, Miao Z, Silverman AP, Ren G, Liu HG, Li PY, Gambhir SS, Cochran JR, Cheng Z . Evaluation of a 64Cu-Labeled Cystine-Knot Peptide Based on Agouti Related Protein for PET of Tumors Expressing αvβ3 Integrin. J Nucl Med. 2010;51(1):251-258.

  • Kimura RH, Miao Z, Cheng Z, Gambhir SS, Cochran JR. Dual Modality PET/NIR Fluorescence Imaging of Angiogenic Tumors in Living Subjects with High Affinity Knottins. Precise Chemical Coupling of Multiple Activities onto a Cystine-Knot Scaffold. Bioconjug Chem. 2010;in press():.

  • Miao Z, Levi J, Cheng Z . Protein Scaffolds Based Molecular Probes for Cancer Molecular Imaging. Amino Acids. 2010;in press():.

  • Benoit MR, Mayer D, Barak Y, Chen IY, Hu W, Cheng Z, Wang SX, Spielman DM, Gambhir SS, Matin A . Visualizing Magnetotactic Bacteria after Colonization of Mouse Tumors with MRI. Clinical Cancer Res. 2009;15():5170-7.

  • Cheng Z, De Jesus OP, Kramer DJ, De A, Webster JM, Gheysens O, Levi J, Namavari M, Wang S, Park JM, Zhang R, Liu H, Lee B, Syud FA, Gambhir SS. 64Cu-Labeled Affibody Molecules for Imaging of HER2 Expressing Tumors. Mol Imaging Biol. 2009;Sep 25. [Epub ahead of print]():.

  • Jiang L, Schipper ML, Li P, Cheng Z* . 123I Labeled Metaiodobenzylguanidine for Diagnosis of Neuroendocrine Tumors . Reports in Medical Imaging. 2009;2():79-89.

  • Kimura RH, Cheng Z, Gambhir SS, Cochran JR. Engineered knottin peptides: a new class of agents for imaging integrin expression in living subjects. Cancer Res. 2009;69(6):2435-42.

  • Miao Z, Ren G, Liu H, Kimura RH, Jiang L, Cochran JR, Gambhir SS, Cheng Z . An Engineered Knottin Peptide Labeled with 18F for PET Imaging of Integrin Expression. Bioconjug Chem. 2009;20(12):2342-7.

  • Namavari M, Cheng Z, Zhang R, De A, Levi J, Hoerner JK, Yaghoubi SS, Syud FA, and Gambhir SS. A Novel method for Direct site-specific Radiolabeling of peptides Using [18F]FDG. Bioconjug Chem. 2009;20():432-436.

  • Ren G*, Liu Z*, Miao Z, Liu H, Jiang L, Subbarayan M, Chin FT, Zhang L, Gambhir SS, Cheng Z. (*equal contribution). Molecular Imaging of Malignant Melanoma using 18F-labeled Metallopeptides. J Nucl Med. 2009;50(11):1865-72.

  • Ren G, Miao Z, Liu H, Jiang L, Limpa-Amara N, Mahmood A,Gambhir SS, Cheng Z. Melanin-Targeted Preclinical PET Imaging of Melanoma Metastasis. J Nuc Med. 2009;50(10):1692-1699.

  • Ren G, Zhang R, Liu Z, Webster JM, Miao Z, Gambhir SS, Syud FA, Cheng Z . A 2-helix small protein labeled with 68Ga for PET imaging of HER2 expression. J Nucl Med. 2009;50(9):1492-9.

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