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Joseph Wu, MD, PhD
Joseph Wu, MD, PhD
Assistant Professor (Medicine & Radiology)
Education:Ph.D., UCLA Department of Molecular & Medical Pharmacology, 1999 - 2004
M.D., Yale, 1997
B.S., UCLA, 1993
Awards: 2008 Junior Faculty Grant - Edward Mallinckrodt, Jr. Foundation

2008-2013 NIH Director's New Innovator Award - National Institutes of Health

2008 Baxter Faculty Scholar

2007 Burroughs Wellcome Fund Career Award for Medical Scientist

2006 ACC/GE Cardiovascular Award

2005 NHLBI-K08 Award

2004 American Society of Nuclear Cardiology grant

2003 GlaxoSmithKline Young Cardiovascular Investigator Grant
Address:Stanford University School of Medicine
Edwards Building R354
Stanford, CA 94305
Phone:(650) 736-2246
Fax:(650) 736-0234
E-mail: joewu@stanford.edu
Research Interests:My lab woks on molecular imaging, gene therapy, and stem cell therapy. We use different molecular markers to better understand stem cell biology in vivo. These include monitoring stem cell survival, proliferation, and differentiation of adult stem cells and human embryonic stem cells. Another component is to integrate genomics and proteomics for biomarker discovery.
Current Labs:Cardiovascular Gene and Cell Therapy
Previous Labs:Multimodality Molecular Imaging Lab
Recent Publications:
  • Cao F, Xie X, Gollan T, Narsinh K, Randall L, Wu JC. Comparisons of Gene Transfer Efficiency in Human Embryonic Stem Cells. Molecular Imaging and Biology.2009; in press(): .

  • Chen IY, Greve JM, Gheysens O, Willmann JK, Rodriguez-Porcel M, Chu P, Sheikh AY, Faranesh AZ, Paulmurugan R, Yang PC, Wu JC, Gambhir SS. Comparison of optical bioluminescence reporter gene and superparamagnetic iron oxide MR contrast agent as cell markers for noninvasive imaging of cardiac cell transplantation. Mol Imaging Biol.2009; 11(3): 178-87.

  • Chen MQ, Xie X, Wilson KD, Giovangrandi L, Wu JC, Kovacs GT. Current-controlled electrical point-source stimulation of embryonic stem cells. Cellular and Molecular Bioengineering.2009; (): in press.

  • Daadi MM, Li Z, Arac A, Grueter BA, Sofilos M, Malenka RC, Wu JC, Steinberg GK.. Molecular and Magnetic Resonance Imaging of Human Embryonic Stem Cell-Derived Neural Stem Cell Grafts in Ischemic Rat Brain. Mol Ther.2009; doi:10.1038/mt.2009.104(): .

  • Li Z, Han Z, Wu JC. Transplantation of Human Embryonic Stem Cell-Derived Endothelial Cells for Vascular Diseases. J of Cell Biochem.2009; PMID: 19097085 (): .

  • Li Z, Lee A, Huang M, Chun H, Chung J, Chu P, Grant H, Yang P, Rosenberg J, Robbins RC, Wu JC. . Imaging Survival and Function of Transplanted Cardiac Stem Cells. JACC.2009; 53(14): 1229-1240.

  • Narsinh K, Cao F, Wu JC. Application of reporter gene imaging for studying human embryonic stem cells in living subjects. Methods in Molecular Biology.2009; 515(): .

  • Sun N, Lee A, Wu JC. Long term non-invasive imaging of embryonic stem cells using reporter genes. Nature Protocols.2009; 4(8): 1192-1201.

  • Sun N, Panetta NJ, Gupta DM, Wilson KD, Lee A, Jia F, Hu S, Cherry AM, Robbins RC, Longaker MT, Wu JC . Feeder-free derivation of induced pluripotent stem cells from adult human adipose stem cells . Proceedings of the National Academy of Sciences of the United States of America.2009; 106(37): 15720-15725.

  • Willmann JK, Paulmurugan R, Rodriguez-Porcel M, Stein W, Brinton TJ, Connolly AJ, Nielsen CH, Lutz AM, Lyons J, Ikeno F, Suzuki Y, Rosenberg J, Chen IY, Wu JC, Yeung AC, Yock P, Robbins RC, Gambhir SS. Imaging gene expression in human mesenchymal stem cells: from small to large animals. Radiology.2009; 252(1): 117-27.

  • Wilson KD, Huang M, Wu JC. Bioluminescence reporter gene imaging of human embryonic stem cell survival, proliferation, and fate. Bioluminescence, Methods in Molecular Biology.2009; 574(): 87-103.

  • Wilson KD, Venkatasubrahmanyam S, Jia F, Sun N, Butte AJ, Wu JC. MicroRNA profiling of human-induced pluripotent stem cells. Stem Cells and Development.2009; 18(5): 749-58.

  • Wilson KD, Wu JC. The miR-145 pluripotency loop in human embryonic stem cells. Cell Science.2009; 6(2): .

  • Yu J*, Huang N*, Wilson KD*, Velotta JB, Mei Huang, Li Z, Lee A, Robbins RC, Cooke JP, Wu JC. nAChRs mediate human embryonic stem cell-derived endothelial cells: proliferation, apoptosis, and angiogenesis. PLoS ONE.2009; 4(9): e7040.

  • Ai L, Rouhanizadeh M, Wu JC, Takabe W, Yu H, Alavi M, Li R, Chu Y, Miller J, Heistad DD, Hsiai TK. Shear stress influences spatial variations in vascular Mn-SOD expression: implication for LDL nitration. Am J Physiol Cell Physiol.2008; 294(6): C1576-85.

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