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| JiangHong Rao |
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Member, MIPS
Assistant Professor of Radiology and, by courtesy, of Chemistry | |
| Education: | 1991 B.S. Peking University
1994 M.S. Rutgers, the State Unviersity of New Jersey
1999 Ph.D. Harvard University |
| Awards: | 1999-2001 Damon Runyon Cancer Fund Merck Fellow
2002-2007 Burroughs Wellcome Fund Career Award at the Scientific Interface
2002-2003 UCLA Frontiers of Sciences Seed Grant |
| Address: | Molecular Imaging Program at Stanford
Department of Radiology
Stanford School of Medicine
Edwards Bld. Rm R-356
300 Pasteur Dr.
Stanford, CA 94305-5324 |
| Phone: | (650) 736-8563 |
| E-mail: | jrao@stanford.edu |
| Research Interests: | Our general interest focuses on the development of molecular probes that are able to monitor specific biological processes under physiological settings. We are combining synthetic and physical organic chemistry, radiochemistry, and molecular biology together with imaging techniques such as fluorescence microscopy and positron emission tomography (PET). Current ongoing projects are:
- developing a multimodality (optical and microPET) reporter gene for imaging gene expression;
- visualizing RNA splicing activity in vivo;
- imaging endogenous gene expression;
- imaging kinase function in vivo.
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| Current Labs: | Cellular and Molecular Imaging Lab (CMIL)
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| Recent Publications: |
- So MK, Gowrishankar G,Hasegawa S,Chung JK and Rao J. Imaging Target mRNA and siRNA-Mediated Gene Silencing In Vivo with Ribozyme-Based Reporters. ChemBiochem.2008; 9(16): 2682-2691.
- Dragulescu-Andrasi A, Rao JH. Chemical labeling of protein in living cells. ChemBioChem.2007; 8(10): 1099-1101.
- Gowrishankar G and Rao J. Visualizing RNA splicing in vivo. Molecular Biosystems.2007; 3(5): 301-7.
- Gowrishankar G, Rao J. Visualizing RNA splicing in vivo. Molecular Biosystems.2007; 3(5): 301-7.
- Rao J, Dragulescu-Andrasi A, Yao H. Fluorescence imaging in vivo: recent advances. Curr. Opin. Biotech.2007; 18(1): 17-15.
- Cai W, Rao J, Gambhir SS, Chen X. How molecular imaging is speeding up anti-angiogenic drug development. Mol. Cancer Ther..2006; 5(): 2624-2633.
- Hasegawa S, Gowrishankar G and Rao J. Detection of mRNA by a split-ribozyme reporter. ChemBiochem.2006; 7(6): 925-28.
- So MK, Loening AM, Gambhir SS, Rao J. Creating self-illuminating quantum dot conjugates. Nat. Prot..2006; 1(3): 1160-1164.
- So MK, Xu C, Loening AM, Gambhir SS, Rao J. Self-illuminating quantum dot conjugates for in vivo imaging. Nature Biotechnology.2006; 24(): 339-43.
- Zhang Y, So MK, Loening AM, Yao H, Gambhir SS, Rao J. HaloTag protein-mediated specific conjugation of bioluminescent proteins to quantum dots. Angew. Chem. Int. Ed. Engl..2006; 45(30): 4936-4940.
- Zhang Y, So MK, Rao J. Protease-Modulated Cellular Uptake of Quantum Dots. Nano Lett.2006; 6(): 1988-1992.
- BG Xing, JH Rao.. Imaging Gene Expression with a Cell-permeable Near Infrared beta-Lactamase Substrates.. J. Am, Chem, Soc.2005; 127(12): 4158-4159.
- Hasegawa S, Choi JW, Rao J. Single-cell detection of trans-splicing ribozyme in vivo activity. Journal of American Chemical Society.2004; 126(23): 7158-7159.
- Gao W, Xing B, Tsien RY, Rao J. Novel fluorogenic substrates for imaging b-lactamase gene expression. Journal of American Chemical Society.2003; 125(): 11146-11147.
- Hasegawa S, Jackson WC, Tsien RY, Rao J. Imaging Tetrahymena ribozyme splicing activity in single live mammalian cells. PNAS.2003; 100(25): 14892-14896
14892-14896.
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