Research Project 1 - Development and Validation of Sensors for Imaging Protein Phosphorylation in Living Subjects
Research Project 2 - Multi-Modality Imaging of Oncogene-Induced Tumorigenesis
Research Project 3 - Dual Biotherapy for the Treatment of Malignancy
Research Project 4 - PET Imaging of Brain Tumor Angiogenesis and Anti-Angiogenic Treatment
SPECIALIZED RESOURCES
Specialized Resource 1 - Chemistry/Radiochemistry Resource
Specialized Resource 2 - Flow Cytometry Resource
Specialized Resource 3 - Small Animal Imaging Resource
- Tim Doyle, PhD
- Laura Pisani, PhD
Specialized Resource 4 - Quantitation and Visualization Resource
- Frezghi Habte, PhD
- Tiffany Liu, PhD
DEVELOPMENTAL PROJECTS
YEAR 1 - 2005-2006
Developmental Project 1 - Multimodality Imaging of mRNA in Living Animals
- Gayatri Gowrishankar, PhD
Developmental Project 2 - In vivo Imaging of Brain Tumor Cellular Dynamics Using Fluorescence Microendoscopy
Developmental Project 3 - Development of Small Animal Conformal Therapy
Developmental Project 4 - PET Imaging of Tumor Vasculature with 18F Labeled VEGF
YEAR 2 - 2006-2007
Developmental Project 1 - Multimodality Imaging of mRNA in Living Animals
Developmental Project 2 - Optically Coupled Readout Front-End for MR-Compatible PET Instrumentation
Developmental Project 3 - Development of Small Animal Conformal Therapy
Developmental Project 4 - Encapsulated Gold Contrast Agent for CT Imaging of Tumors
- Arundhuti C. Ganguly, PhD
YEAR 3 - 2007-2008
Developmental Project 1 - Use of Magnetic Producing Bacteria for Tumor Targeting and Enhancing MRI Contrast
- Michael Benoit, PhD
- Yoram Barak, PhD
Developmental Project 2 - Molecular Imaging of Tumor Matrix Metalloproteinase Expression Using 18F Labeled Chlorotoxin
- Zhe Liu, PhD
- Zhengming Xiong, PhD
Developmental Project 3 - Magnetic Resonance Spectroscopic Imaging of Hyperpolarized 13C-labeled Pyruvate
Developmental Project 4 - Imaging Cancer Patient with Manganese-Enhanced MRI
YEAR 4 - 2008-2009
Developmental Project 1 - Synthesis and Use of 18F-fluoro-9-B-D-arabinofuranosylguanine as an Imaging Agent for the Detection of Diseases of T cell Origin
Developmental Project 2 - A Novel Rhenium Cyclized Peptide for Pre-clinical Imaging of Melanoma Metastases
Developmental Project 3 - Molecular Ultrasound for Monitoring Anti-Angiogenic Cancer Treatment: Comparison with PET-CT
Developmental Project 4 - Imaging Cancer Pain with Manganese-Enhanced MRI
YEAR 5 - 2009-2010
Developmental Project 1 - Gene Therapy for Hepatocullular Carcinoma: Development of a Readily Translatable Non-Viral Vector
- Young Kim
- Luke Higgins
- Regina Katzenberg
Developmental Project 2 - Synthesis and Use of 18F-fluoro-9-B-D-arabinofuranosylguanine as an Imaging Agent for the Detection of Diseases of T cell Origin
Developmental Project 3 - 1 mm Resolution Laser-coupled PET Detector for Simultaneous PET/MR of the Breast
Developmental Project 4 - Molecular Image-Based Clinical Management of Head and Neck Cancers
YEAR 6 - 2010-2011
Developmental Project 1 - Nanoparticle-Mediated Delivery of a Novel Prodrug Regiment to Prostate Cancer
Developmental Project 2 - Clincally-Translatable Integrative Quantitative Functional and Molecular Ultrasonic Imaging Approach for Monitoring Anti-Vascular Cancer Therapy
Developmental Project 3 - Engineering Stable Knottin Peptides as a New Class of Molecular Imaging Agents
Developmental Project 4 - Development of a Novel Gadolinium-Based MRI Contrast Agent for Tracking Cancer Cells
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