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Title: Monitoring Response to Targeted Therapy in Non-Small Cell Lung Cancer using 18F FPPRGD2 PET/CT and In-Vitro Diagnostics
The specific aims of the current research proposal are to apply novel methods for predicting and monitoring response to anti-cancer treatments. |
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Title: Image-Guided Resection to Improve Outcome for Children with Medulloblastoma
The specific aims of this project is to improve tumor visualization and localization. We aim to refine existing peptide-based probes, and identify new molecular probes that can be applied topically to label tumor cell-surface markers in human medulloblastoma intra-operatively. |
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Title: Multi-Modality Imaging of Oncogene Addiction
This project aims to use mathematical and statiscial modeling together with quantitative molecular imaging to predict very early after the initiation of a therapy whether cancer patients will respond to targeted oncogene inactivation. |
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Title: Development of Enzyme-Activated PET and MRI Probes for Cancer Imaging
The general goal of this research is to develop positron emission tomography (PET) and magnetic resonance imaging (MRI) based molecular imaging systems to image cancer-specific enzymatic activity of proteases in vivo. |