Research Associates

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Education:

Postdoctoral fellow, Johns Hopkins University
PhD. Wesleyan university
B.S. Beijing Univ. of Aero. & Astro.

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Contact Information:

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Research Interests:

1. Design and synthesis of the candidate probes and related precursors suitable for introduction of a radiolabel for molecular imaging.
2. Design and synthesis for molecular probes for in vivo imaging of diseases.
3. Coordination chemistry of Mn(II) and Cu(II).
4. Protein ligand interaction.
5. The effect of impurities on crystal growth.

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Recent Publications:

1. Wang,S.,Amornwittawat,N.;Banatlao,J.;Chung,M.; Kao,Y.; Wen, X.. Hofmeister Effects of Common Monovalent Salts on the Beetle Antifreeze Protein Activity. J. Phys. Chem. B. (in press).
2. Wang,S;Amornwittawat,N.;Juwita,V.;Kao,Y.;Duman,J. G.; Pascal,T. A.;Goddard III,W. A.;Wen, X. Arginine, a key residue for the enhancing ability of an antifreeze protein of the beetle Dendroides canadensis. Biochemistry (in press).
3. Natarajan, A.; Gowrishankar, G.; Nielsen, C. H.; Wang, S.; Lagaru, A; Goris, M. L. Positron Emission Tomography of 64Cu-DOTA-Rituximab in a Transgenic Mouse Model Expressing Human CD20 for Clinical Translation to Image NHL. Mol. Imaging Biol. 2012 (in press).
4. Wen, X.; Wang, S.; Amornwittawat, N; Houghton, E. A.; Sacoo, M. A. Interaction of Reduced Nicotinamide Adenine Dinucleotide with an Antifreeze Protein from Dendroides canadensis: Mechanistic Implication of Antifreeze Activity Enhancement. Mol. Recog., 2011;24:1025-1032.
5. Cheng, Z.; De Jesus, O.; Kramer, D.; De, A.; Webster, J.; Gheysens, O.; Levi, J.; Namavari, M.; Wang, S.; Park, J.; Zhang, R.; Liu, H.; Lee, B.; Syud, F. A.; Gambhir, S. S. 64Cu-Labeled Affibody Molecules for Imaging of HER2 Expressing Tumors, Mol. Imaging Biol., 2010;12:316-324.
6. Amornwittawat, M.; Wang, S.; Banatlao, J.; Chung, M.; Velasco, E.; Duman, J. G.; Wen, X. Effects of Polyhydroxy Compounds on Beetle Antifreeze Protein Activity. BBA, 2009;1794(2):341-346.
7. Wang, S.; Amornwittawat, N.; Banatlao, J.; Chung, M.; Kao, Y.; Wen, X. Hofmeister Effects of Common Monovalent Salts on the Beetle Antifreeze Protein Activity. J. Phys Chem B, 2009;113:13891-13894.
8. Wang, S.; Amornwittawat, N.; Juwita, V.; Kao, Y.; Duman, J. G.; Pascal, T. A.; Goddard, W. A.; Wen, X. Arginine, a Key Residue for the Enhancing Ability of an Antifreeze Protien of the Beetle Dendroides Canadensis. Biochemistry, 2009;48:9696-9703.
9. Wang, S.; Westmoreland, T. D. Correlation of Relaxivity with Coordination Number in Six-, Seven-, and Eight Coordinate Mn(II) Complexes of Pendant Arm Cyclen Derivations. Inorg. Chem. 2009;48(2):719-727.
10. Amornwittawat, N.; Wang, S.; Duman, J. G.; Wen, X. Polycarboxylates Enhance Beetle Antifreeze Protein Activity. Biochim. Biophys Acta, Proteins & Proteomics, 2008;1784(12):1942-1948.