Dose % Response LOG Dose % Response
2 10 0.30103 10
4 20 0.60205999 20
5 25 0.69897 25
8 40 0.90308999 40
10 50 1 50
20 70 1.30103 70
30 85 1.47712125 85
50 90 1.69897 90

Now one can linearize this plot in order to obtain the dose at which 50% response occurs. This is done by doing a linear regression on the LOG dose vs. (Response-Median).

LOG Dose % Response % Response Median (% Response-Median)
0.30103 10 45 -35
0.60205999 20 -25
0.69897 25 -20
0.90308999 40 -5
1 50 5
1.30103 70 25
1.47712125 85 40
1.69897 90 45

   

9:1