Bioengineering/Radiology 222B - Winter 2011
Chemistry of Molecular Probes for Imaging in Living Subjects
Course Syllabus
CLASSES: Mondays & Fridays 9-10:50 AM, LK 209 |
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| Week | Monday | Instructor | Friday | Instructor |
| 1 | 1/3 | Overview and reporter proteins C. Contag  Lecture notes |
1/7 | Pharmacology and overcoming barriers to delivery P. Wender |
| 2 | 1/10 | Molecular transporters for delivery of imaging agents P. Wender |
1/14 | High throughput screens for finding new probes and targets F. Cochran Lecture notes
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| 3 | 1/17 | School holiday: no class | 1/21 | Peptide probes for imaging F. Cochran Lecture notes |
| 4 | 1/24 | Contrast and Contrast Agents in X-ray Imaging E. Graves MIPP CH 4: Principles of micro x-ray computed tomography |
1/28 | Radiochemistry part 1 F. Chin Lecture notes |
| 5 | 1/31 | Chemical Control of reporters and therapeutic proteins T. Wandless Lecture notes
MIPP CH 31: Chemical Biology Approaches to Molecular Imaging MIPP CH 39: Protein Engineering |
2/4 | Targeting proteases for imaging M. Bogyo Lecture notes
MIPP CH 8: Optical Multimodality MIPP CH 10: Fluorescence Tomography MIPP CH 23: Targeted Antibodies and Peptides MIPP CH 26: Optical Imaging Agents MIPP CH 31: Chemical Biology Approaches to Molecular Imaging MIPP CH 47: Fluorescence Reporters/Activatable Cell Penetrating Peptides MIPP CH 48: Imaging of Signaling Pathways MIPP CH 49: Molecular and Functional Imaging of the Tumor Microenvironment MIPP CH 56: Molecular Imaging of Atherosclerosis MIPP CH 63: Rheumatoid Arthritis MIPP CH 65: Imaging in Asthma |
| 6 | 2/7 | Radiochemistry part 2 F. Chin Lecture notes
MIPP CH 20: Radiochemistry of SPECT MIPP CH 21: Nanochemistry for Molecular Imaging |
2/11 | Optical reporters - principles M. Lin Lecture notes
MIPP CH 26: Optical Imaging Agents MIPP CH 47: Fluorescence Reporters/Activatable Cell Penetrating Peptides |
| 7 | 2/14 | Optical reporters - practice M. Lin Lecture notes |
2/18 | Novel strategies in optical imaging agents J. Rao Lecture notes |
| 8 | 2/21 | School holiday: no class | 2/25 | Particles and probes J. Rao |
| 9 | 2/28 | Hyperpolarized compounds for MRI D. Spielman Lecture notesMIPP CH 24: Hyperpolarized 13C magnetic resonance imaging ' Principles and applications MIPP CH 52: MRS Treatment Response and Detection |
3/4 | Antibodies and their derivatives as imaging probes A. Wu Lecture notes
MIPP CH 23: Targeted Antibodies and Peptides MIPP CH 39: Protein Engineering |
| 10 | 3/7 | Novel MRI probes B. Rutt Lecture notes |
3/11 | MRI Probes for cell trafficking B. Rutt Lecture notes |
| Final Presentations: March 18, 2011 Li Ka Shing, 3rd floor - Room LK306 |
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