MIPS Molecular Imaging Program at Stanford

Bioengineering/Radiology 222A
Course Syllabus

Classes: Monday & Friday, 9:00 - 10:50, AM Clark Center S361

09/25 Introduction to Molecular Imaging [ Part 1 | Part 2 ] Dr. Levin
09/29 Optics (physics): Tissue optics [ Download PDF - 17.3MB ]pdf icon

Biomedical Photonics Handbook [ Download PDF - 7MB ]pdf icon
  • Tromberg B, et al. Non-Invasive In Vivo Characterization of Breast Tumors Using Photon Migration Spectroscopy. Neoplasia 2000; 2(1-2):26-40.
    [ Download PDF - 2.1MB ] pdf icon
Dr. Contag
10/02 Optics (physics): 3D fluorescence imaging [ Download PDF - 12.5MBB ] pdf icon Dr. Graves
10/06 Optics Application: Intervital Optical Neuroimaging [ Download PDF - 19.4MB ] pdf icon Dr. Schnitzer
10/09 Optics Application: Optical Reporter Genes [ Download PDF - 5.7MB ] pdf icon
  • Tsien RY. The Green Fluorescent Protein. Annu. Rev. Biochem. 1998; 67:509-44.
    [ Download PDF - 545KB ] pdf icon
  • Contag C, Bachmann MH. Advances in In Vivo Bioluminescence Imaging of Gene Expression. Annu. Rev. Biomed. Eng. 2002; 4:235-60.
    [ Download PDF - 353KB ]

    pdf icon
Dr. Contag
10/13 Chemistry of Fluorescent Probes [ Download PDF - 8.3MB ] pdf icon
  • Frangioni JV. In vivo near-infrared fluorescence imaging. Curr Opin Chem Biol. 2003;7(5):626-34.
    [ Download PDF - 231KB ] pdf icon
  • Gao X, Yang L, Petros JA, Marshall FF, Simons JW, Nie S. In vivo molecular and cellular imaging with quantum dots. Curr Opin Biotechnol. 2005 Feb;16(1):63-72.
    [ Download PDF - 316KB ] pdf icon
  • So MK, Xu C, Loening AM, Gambhir SS, Rao J. Self-illuminating quantum dot conjugates for in vivo imaging. Nature Biotechnology 2006; 24(3):339-43.
    [ Download PDF - 468KB ]pdf icon
Dr. Rao
10/16 MR Basic Principles [ Download PDF - 1.8MB ]pdf icon Dr. McConnell
10/20 Molecular Imaging with MR [ Download PDF - 7.7MB ]pdf icon Dr. Moseley
10/23 Neuroimaging by MR [ Download PDF - 19.3MB ]pdf icon Dr. Moseley
10/27 Cardiovascular MRI/Targeted MRI Contrast Agents [ Download PDF - 6.1MB ]pdf icon Dr. McConnell
10/30 Vascular imaging/ angiogenesis/ targeted vascular imaging [ Download PDF - 7.6 MB ]pdf icon Dr. Guccione
11/03 Radiochemistry [ Download PDF - 3.0MB ]pdf icon Dr. Chen
11/06 PET: Instrumentation, Methods, and Applications [ Download PDF - 17.5MB ] pdf icon
Principles of Computerized Tomographic Imaging. Kak, Slaney, IEEE Press, 1988.

Physics in Nuclear Medicine. Cherry, Sorenson, Phelps, 3rd Edition. Saunders, 2003.

Dr. Levin
November 6, 2006 - Midterm Exam

7:00 PM
Place: Learning Center (Room P083) of the Lucas Magnetic Imaging Center.
Direction: Lucas is linked to the MSLS building, at the corner of Welch Road and Pastuer Drive.
Take the outside stairs down to the first floor, and the Learning Center is at your left.

11/10 Multimodality Molecular Imaging of Integrin Expression [ Download PDF - 9.6MB ] pdf icon
Logan J. Graphical analysis of PET data applied to reversible and irreversible tracers. Nucl Med Biol 2000;27:661-670.
[ Download PDF - 725KB ]pdf icon

Cai W, Gambhir SS, Chen X. Multimodality tumor imaging targeting integrin alpha(v)beta(3). BioTechniques.2005; 39:S6-S17.
[ Download PDF - 9.2MB ]pdf icon

Dr. Chen
11/13 SPECT: Instrumentation, Methods and Applications [ Download PDF - 23.6MB ] pdf icon
Principles of Computerized Tomographic Imaging. Kak, Slaney, IEEE Press, 1988.

Physics in Nuclear Medicine. Cherry, Sorenson, Phelps, 3rd Edition. Saunders, 2003.

Dr. Levin
11/17 Imaging of Apoptosis [ Download PDF - 6.3MB ] pdf icon
  1. Belhocine TZ, Tait JF, Vanderheyden JL, Li C, Blankenberg FG. Nuclear medicine in the era of genomics and proteomics: lessons from annexin V. J Proteome Res. 2004 May-Jun;3(3):345-9.
    [ Download PDF - 156KB ] pdf icon
  2. Blankenberg FG. Recent advances in the imaging of programmed cell death. Curr Pharm Des. 2004;10(13):1457-67. Review.
    [ Download PDF - 296KB ] pdf icon
  3. Blankenberg F, Mari C, Strauss HW. Imaging cell death in vivo. Q J Nucl Med. 2003 Dec;47(4):337-48. Review.
    [ Download PDF - 272KB ] pdf icon
  4. Lahorte CM, Vanderheyden JL, Steinmetz N, Van de Wiele C, Dierckx RA, Slegers G. Apoptosis-detecting radioligands: current state of the art and future perspectives. Eur J Nucl Med Mol Imaging. 2004 Jun;31(6):887-919.
    [ Download PDF - 428KB ] pdf icon
  5. Kolodgie FD, Petrov A, Virmani R, Narula N, Verjans JW, Weber DK, Hartung D, Steinmetz N, Vanderheyden JL, Vannan MA, Gold HK, Reutelingsperger CP, Hofstra L, Narula J. Targeting of apoptotic macrophages and experimental atheroma with radiolabeled annexin V: a technique with potential for noninvasive imaging of vulnerable plaque. Circulation. 2003 Dec 23;108(25):3134-9.
    [ Download PDF - 384KB ] pdf icon
  6. Blankenberg FG, Strauss HW. Nuclear medicine applications in molecular imaging. J Magn Reson Imaging. 2002 Oct;16(4):352-61. Review.
    [ Download PDF - 288KB ] pdf icon
Dr. Blakenberg
11/27 Application of Molecular Imaging in Stem Cell Therapy [ Download PDF - 1.4MB ]pdf icon Dr. Wu
12/01 Applications of Molecular Imaging in Radiation Therapy (1) [ Download PDF - 10.6MB ]pdf icon Dr. Graves
12/04 Applications of Molecular Imaging in Radiation Therapy (2) [ Download PDF - 1.2MB ]pdf icon Dr. Xing
12/08 Applications of Molecular Imaging in Humans [ Download PDF - 26.5MB ]pdf icon Dr. Gambhir
TBD Tour of Small Animal Imaging Facility Dr. Doyle
Monday, December 11, 2006 - Final Exam

9:00 - 11:00 AM
Place: Learning Center (Room P083) of the Lucas Magnetic Imaging Center.
Direction: Lucas is linked to the MSLS building, at the corner of Welch Road and Pastuer Drive.
Take the outside stairs down to the first floor, and the Learning Center is at your left.

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